A supramolecular ion channel based on amphiphilic cholic acid derivatives

被引:22
|
作者
Kobuke, Y
Nagatani, T
机构
[1] Nara Inst Sci & Technol, Grad Sch Mat Sci, Nara 6300101, Japan
[2] Shizuoka Univ, Fac Engn, Hamamatsu, Shizuoka 4328514, Japan
关键词
D O I
10.1246/cl.2000.298
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Cholic acid was modified so as to represent the simplest expression of an artificial supramolecular ion channel by converting three hydroxyls to methyl ethers and a carboxyl to a methylene(trimethyl)ammonium grouping. It gave stable single channel currents showing several conductance values in planar bilayer lipid membrane.
引用
收藏
页码:298 / 299
页数:2
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