Management of cardiovascular diseases in HIV/AIDS patients

被引:3
|
作者
Ashwitha, Santoshi K. [1 ]
Jacob, Preethi A. [1 ]
Ajaj, Abdullah [1 ]
Shirke, Manasi M. [1 ]
Harky, Amer [2 ,3 ,4 ]
机构
[1] Queens Univ Belfast, Sch Med, Dept Med, Belfast, Antrim, North Ireland
[2] Liverpool Heart & Chest Hosp, Dept Cardiothorac Surg, Thomas Dr, Liverpool L14 3PE, Merseyside, England
[3] Univ Liverpool, Dept Cardiovasc Sci, Liverpool Heart & Chest Hosp, Liverpool, Merseyside, England
[4] Alder Hey Children Hosp, Dept Cardiac Surg, Liverpool, Merseyside, England
关键词
cardiovascular disease; heart; immunodeficiency; immunosuppression; HIV-INFECTED PATIENTS; ANTIRETROVIRAL THERAPY; IMMUNODEFICIENCY-SYNDROME; HEART-FAILURE; RISK; MANIFESTATIONS; PATHOPHYSIOLOGY; ASSOCIATION; DYSFUNCTION; MORTALITY;
D O I
10.1111/jocs.15213
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Human immunodeficiency virus (HIV) infection/acquired immunodeficiency syndrome, a pandemic in the current population causes severe weakness of the body's immune system making the infected patient more vulnerable to life-threatening conditions. The disease predisposes the infected patient to several cardiovascular diseases and cerebrovascular diseases such as heart failure and stroke. The decline in CD4 cells following HIV infection, vulnerability to opportunistic infections and underlying HIV pathology plays a major role in the development of cardiovascular manifestations, and treatment targeting cardiomyopathy in this specific patient subset is not well recognized. Patients living with HIV (PLWH) also experience discrimination in receiving cardiovascular disease care and this needs to be addressed by strengthening frameworks for monitoring and providing nonjudgmental healthcare. This review aims to study the profile of the cardiovascular disease in HIV patients, treatment, and provide evidence of the disparity in the provision of healthcare with regard to PLWH.
引用
收藏
页码:236 / 243
页数:8
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