New-onset epilepsy in the elderly: Challenges for the internist

被引:35
|
作者
Ghosh, Sayantani [1 ]
Jehi, Lara E. [1 ,2 ,3 ]
机构
[1] Cleveland Clin, Epilepsy Ctr, Cleveland, OH 44195 USA
[2] Cleveland Clin, Clin Res Unit, Cleveland, OH 44195 USA
[3] Case Western Reserve Univ, Lerner Coll Med, Cleveland Clin, Cleveland, OH 44106 USA
关键词
NONCONVULSIVE STATUS EPILEPTICUS; NURSING-HOME RESIDENTS; ANTIEPILEPTIC DRUG-USE; ALZHEIMERS-DISEASE; ACUTE STROKE; SEIZURES; POPULATION; MINNESOTA; ROCHESTER; ETIOLOGY;
D O I
10.3949/ccjm.81a.13148
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
New-onset epilepsy in the elderly is difficult to diagnose, owing to atypical presentation, concomitant cognitive impairment, similarities with other common disorders, and nonspecific changes on electroencephalography (EEG). Its management is also challenging because of its deranging physiology, comorbidities, and polypharmacy. Antiepileptic drugs must be carefully chosen and closely monitored. Support of the patient and caregiver is key.
引用
收藏
页码:490 / 498
页数:9
相关论文
共 50 条
  • [1] New-onset epilepsy in the elderly
    Vu, Lily Chi
    Piccenna, Loretta
    Kwan, Patrick
    O'Brien, Terence J.
    [J]. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2018, 84 (10) : 2208 - 2217
  • [2] Management of new-onset epilepsy in the elderly
    Amir M. Arain
    Bassel W. Abou-Khalil
    [J]. Nature Reviews Neurology, 2009, 5 : 363 - 371
  • [3] Management of new-onset epilepsy in the elderly
    Arain, Amir M.
    Abou-Khalil, Bassel W.
    [J]. NATURE REVIEWS NEUROLOGY, 2009, 5 (07) : 363 - 371
  • [4] The causes of new-onset epilepsy and seizures in the elderly
    Liu, Shasha
    Yu, Weihua
    Lu, Yang
    [J]. NEUROPSYCHIATRIC DISEASE AND TREATMENT, 2016, 12 : 1425 - 1434
  • [5] TRENDS IN THE TREATMENT OF NEW-ONSET EPILEPSY IN THE ELDERLY
    Royer-Perron, L.
    Deacon, C.
    Perrier-Ferland, L-C
    Bocti, C.
    [J]. EPILEPSIA, 2013, 54 : 77 - 77
  • [6] Comparison Of New-Onset And Persistent Epilepsy In The Elderly
    Kim, D. W.
    Oh, J.
    [J]. EPILEPSIA, 2019, 60 : 79 - 79
  • [7] Comparison of new-onset and persistent epilepsy in the elderly
    Kim, Dong Wook
    Oh, Jeeyoung
    [J]. ACTA NEUROLOGICA SCANDINAVICA, 2019, 139 (04): : 395 - 398
  • [8] INTERICTAL EPILEPTIFORM DISCHARGES IN NEW-ONSET EPILEPSY IN THE ELDERLY
    Toyota, T.
    Akamatsu, N.
    [J]. EPILEPSIA, 2014, 55 : 63 - 63
  • [9] Clinical characteristics and treatment responses in new-onset epilepsy in the elderly
    Tanaka, Akihiro
    Akamatsu, Naoki
    Shouzaki, Taisaku
    Toyota, Tomoko
    Yamano, Mitsuhiko
    Nakagawa, Masanori
    Tsuji, Sadatoshi
    [J]. SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, 2013, 22 (09): : 772 - 775
  • [10] Neuronal intranuclear inclusion disease manifesting with new-onset epilepsy in the elderly
    Toyota, Tomoko
    Huang, Zhe
    Nohara, Souhei
    Okada, Kazumasa
    Kakeda, Shingo
    Korogi, Yukunori
    Nakayama, Toshiyuki
    Sone, Jun
    Sobue, Gen
    Adachi, Hiroaki
    [J]. NEUROLOGY AND CLINICAL NEUROSCIENCE, 2015, 3 (06): : 238 - 240