COMPARISON OF HUMAN METAPNEUMOVIRUS INFECTION WITH RESPIRATORY SYNCYTIAL VIRUS INFECTION IN CHILDREN

被引：7

作者：

Zhang, Sean X. ^{[2
,3
]}

Tellier, Raymond ^{[3
]}

Zafar, Rubeena

Cheung, Rose

Adachi, Dena

Richardson, Susan E. ^{[1
,2
,3
]}

机构：

[1] Hosp Sick Children, Dept Paediat Lab Med, Div Microbiol, Toronto, ON M5G 1X8, Canada

[2] Ontario Agcy Hlth Protect & Promot, Publ Hlth Labs Toronto, Toronto, ON, Canada

[3] Univ Toronto, Dept Lab Med & Pathobiol, Toronto, ON, Canada

来源：

PEDIATRIC INFECTIOUS DISEASE JOURNAL | 2009年 / 28卷 / 11期

关键词：

human metapneumovirus; respiratory syncytial virus; PCR;

D O I：

10.1097/INF.0b013e3181aa6853

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We aimed to validate a direct immunofluorescence assay (DFA) for the detection of human metapneumovirus (hMPV) from nasal swabs and to determine the incidence and clinical features of this viral infection in a pediatric population. One hundred twenty-one of 3026 nasal swabs were positive for hMPV by DFA (4.0%). Compared with reverse transcriptase polymerase chain reaction, the sensitivity and specificity of DFA were 90%, and 100%, respectively. Compared with RSV, hMTV infection was more common in children with congenital abnormalities, particularly those with cardio-pulmonary dysplasia and was associated with an increased ventilatory requirement.

引用

页码：1022 / 1024

页数：3

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