Intermolecular (4+3) cycloadditions of aziridinyl enolsilanes

被引：17
|
作者：
Lam, Sze Kui
Lam, Sarah
Wong, Wing-Tak
Chiu, Pauline [1 ]
机构：
[1] Univ Hong Kong, Dept Chem, Hong Kong, Hong Kong, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2014年 / 50卷 / 14期
关键词：
OXYALLYL CATIONS; EPOXY ENOLSILANES;
D O I：
10.1039/c3cc48266a
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Upon activation by strong Bronsted acids, aziridinyl enolsilanes undergo (4+3) cycloadditions with dienes to afford aminoalkylated cycloheptenones as products. The use of a highly polar medium such as nitroalkane facilitates high cycloaddition yields of up to 99%. Optically pure aziridinyl enolsilanes react to yield (4+3) cycloadducts with up to 99% ee.
引用
收藏
页码：1738 / 1741
页数：4
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