Cardiovascular Complications of COVID-19 and Associated Concerns: A Review

被引：11
|
作者：
Yu, Wen-Liang [1 ,2 ]
Toh, Han Siong [1 ,3 ]
Liao, Chia-Te [4 ,5 ]
Chang, Wei-Ting [3 ,4 ,6 ]
机构：
[1] Chi Mei Med Ctr, Dept Intens Care Med, Tainan, Taiwan
[2] Taipei Med Univ, Coll Med, Sch Med, Dept Med, Taipei, Taiwan
[3] Natl Cheng Kung Univ, Coll Med, Inst Clin Med, Tainan, Taiwan
[4] Chi Mei Med Ctr, Dept Internal Med, Div Cardiol, 901 Zhonghua Rd, Tainan 710, Taiwan
[5] Natl Cheng Kung Univ, Coll Med, Dept Publ Hlth, Tainan, Taiwan
[6] Southern Taiwan Univ Sci & Technol, Dept Biotechnol, Tainan, Taiwan
来源：
ACTA CARDIOLOGICA SINICA | 2021年 / 37卷 / 01期
关键词：
Cardiovascular injuries; COVID-19; Cytokine storm; Therapies; CORONAVIRUS; INHIBITION; INFECTION; APOPTOSIS; ACE2; TMPRSS2;
D O I：
10.6515/ACS.202101_37(1).20200913A
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
SARS-CoV-2 is the virus that has caused the current coronavirus disease 2019 (COVID-19) pandemic. SARS-CoV-2 is characterized by significantly affecting the cardiovascular system of infected patients. In addition to the direct injuries caused by the virus, the subsequent cytokine storm - an overproduction of immune cells and their activating compounds - also causes damage to the heart. The development of anti-SARS-CoV-2 treatments is necessary to control the epidemic. Despite an explosive growth in research, a comprehensive review of up-to-date information is lacking. Herein, we summarize pivotal findings regarding the epidemiology, complications, and mechanisms of, and recent therapies for, COVID-19, with special focus on its cardiovascular impacts.
引用
收藏
页码：9 / 17
页数：9
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