A phase I and pharmacokinetic (PK) study of the novel mushroom-derived cytotoxin, MGI 114, in combination with irinotecan in patients with advanced cancer.

被引：0
|
作者：
Eckhardt, SG
Kuhn, JG
Britten, CD
Weitman, S
Baker, SD
MacDonald, JR
Newman, A
Smith, S
Von Hoff, DD
Rowinsky, EK
机构：
[1] MGI PHARMA, Minnetonka, MN USA
[2] Canc Therapy & Res Ctr, San Antonio, TX 78229 USA
来源：
CLINICAL CANCER RESEARCH | 1999年 / 5卷
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
319
引用
收藏
页码：3793S / 3793S
页数：1
相关论文
共 50 条
  • [1] A phase I and pharmacokinetic (PK) study of the novel mushroom-derived cytotoxin, MGI114, in patients with advanced cancer
    Eckhardt, SG
    Baker, SD
    Moczygemba, J
    MacDonald, JR
    Smith, S
    Von Hoff, DD
    Rowinsky, EK
    ANNALS OF ONCOLOGY, 1998, 9 : 123 - 123
  • [2] Phase I and pharmacokinetic study of irofulven, a novel mushroom-derived cytotoxin, administered for five consecutive days every four weeks in patients with advanced solid malignancies
    Eckhardt, SG
    Baker, SD
    Britten, CD
    Hidalgo, M
    Siu, L
    Hammond, LA
    Villalona-Calero, MA
    Felton, S
    Drengler, R
    Kuhn, JG
    Clark, GM
    Smith, SL
    MacDonald, JR
    Smith, C
    Moczygemba, J
    Weitman, S
    Von Hoff, DD
    Rowinsky, EK
    JOURNAL OF CLINICAL ONCOLOGY, 2000, 18 (24) : 4086 - 4097
  • [3] A phase I pharmacokinetic study of declopramide in combination with cisplatin in patients with advanced cancer.
    Remick, S
    Dowlati, A
    Robertson, K
    Buchter, C
    Ingalls, S
    Hoppel, C
    Spiro, T
    Makkar, V
    Overmoyer, B
    Gerson, S
    ANNALS OF ONCOLOGY, 2000, 11 : 138 - 138
  • [4] Pharmacokinetic study of the novel platinum agent ZD0473 in combination with gemcitabine: A phase I study in patients with advanced cancer.
    O'Dwyer, PJ
    Stevenson, JP
    Redlinger, M
    Sun, W
    Giantonio, B
    Hahn, S
    Algazy, K
    Burnite, M
    Garcia-Vargas, J
    Roberts, DW
    Oliver, R
    CLINICAL CANCER RESEARCH, 2001, 7 (11) : 3750S - 3750S
  • [5] Phase I and pharmacokinetic study of the farnesyltransferase inhibitor R115777 in combination with irinotecan in patients with advanced cancer
    Cohen, SJ
    Gallo, J
    Lewis, NL
    Alpaugh, RK
    Gentner, L
    Rogatko, A
    Yeslow, G
    Schol, J
    Verhaeghe, T
    Zannikos, P
    Palmer, PA
    Weiner, LM
    Meropol, NJ
    CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2004, 53 (06) : 513 - 518
  • [6] Phase I and pharmacokinetic study of the farnesyltransferase inhibitor R115777 in combination with irinotecan in patients with advanced cancer
    Steven J. Cohen
    James Gallo
    Nancy L. Lewis
    R. Katherine Alpaugh
    Louis Gentner
    André Rogatko
    Gwen Yeslow
    Jessie Schol
    Tom Verhaeghe
    Peter Zannikos
    Peter A. Palmer
    Louis M. Weiner
    Neal J. Meropol
    Cancer Chemotherapy and Pharmacology, 2004, 53 : 513 - 518
  • [7] A phase I and pharmacokinetic (PK) study of high dose selenomethionine (SLM) in combination with irinotecan (IRI) in patients with advanced solid tumors.
    Rustum, Y
    Pendyala, L
    Creaven, PJ
    Smith, P
    Azrak, R
    Cao, S
    Durrani, F
    Lawrence, DD
    Badmaev, V
    Diane, NC
    Fakih, MG
    JOURNAL OF CLINICAL ONCOLOGY, 2005, 23 (16) : 154S - 154S
  • [8] Phase I and pharmacokinetic study (PK) of the combination of multitargeted antifolate pemetrexed (ALIMTA) with irinotecan (CPT-11) in patients with advanced malignancies
    Beeram, M
    Hammond, L
    Schwartz, G
    Patnaik, A
    Tolcher, A
    Simmons, C
    Renshaw, G
    Rowinsky, E
    EUROPEAN JOURNAL OF CANCER, 2002, 38 : S24 - S25
  • [9] A phase I study of irinotecan in combination with amrubicin for advanced lung cancer patients
    Kaneda, Hiroyasu
    Kurata, Takayasu
    Tamura, Kenji
    Uejima, Hisao
    Nakagawa, Kazuhiko
    Fukuoka, Masahiro
    ANTICANCER RESEARCH, 2006, 26 (3B) : 2479 - 2485
  • [10] Phase I and pharmacokinetic study of combination chemotherapy using irinotecan and paclitaxel in patients with lung cancer
    Asai, Gyo
    Yamamoto, Nobuyuki
    Kurata, Takayasu
    Tamura, Kenji
    Uejima, Hisao
    Nakagawa, Kazuhiko
    Fukuoka, Masahiro
    JOURNAL OF THORACIC ONCOLOGY, 2006, 1 (03) : 226 - 230
12345