B-1 cells: orthodox or conformist?

被引：28

作者：

Su, IH ^{[1
]}

Tarakhovsky, A ^{[1
]}

机构：

[1] Univ Cologne, Inst Genet, Lab Lymphocyte Signaling, D-50931 Cologne, Germany

来源：

CURRENT OPINION IN IMMUNOLOGY | 2000年 / 12卷 / 02期

关键词：

D O I：

10.1016/S0952-7915(99)00071-0

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

B-1 cells differ from conventional peripheral B cells (B-2) by anatomical location, surface marker expression, antibody repertoire and growth properties. The lineage hypothesis of B-1 cell development attributes the properties of B-1 cells to their unique origin. The induced differentiation hypothesis suggests the surface-immunoglobulin-driven development of B-1 cells from common B-1/B-2 cell progenitors, In both models self-antigen-induced signalling plays the central role in positive selection of B-1 cells, The ability of B-1 cells to be positively selected by self-antigens raises questions about the mechanism of this phenomenon.

引用

页码：191 / 194

页数：4

共 50 条

[1] B-1 phagocytes: the myeloid face of B-1 cells
Popi, Ana Flavia
B-1 CELL DEVELOPMENT AND FUNCTION, 2015, 1362 : 86 - 97
[2] To B-1 or not to B-1
Henry H Wortis
Nature Immunology, 2017, 18 : 365 - 366
[3] Autoregulatory B-1 cells
Sindhava, Vishal J.
Bondada, Subbarao
JOURNAL OF IMMUNOLOGY, 2009, 182
[4] B-1 cells and autoimmunity
Murakami, M
Honjo, T
IMMUNOGLOBULIN GENE EXPRESSION IN DEVELOPMENT AND DISEASE, 1995, 764 : 402 - 409
[5] To B-1 or not to B-1
Wortis, Henry H.
NATURE IMMUNOLOGY, 2017, 18 (04) : 365 - 366
[6] Human B-1 Cells and B-1 Cell Antibodies Change With Advancing Age
Rodriguez-Zhurbenko, Nely
Quach, Tam D.
Hopkins, Thomas J.
Rothstein, Thomas L.
Hemandez, Ana M.
FRONTIERS IN IMMUNOLOGY, 2019, 10
[7] Formation of B-1 B Cells from Neonatal B-1 Transitional Cells Exhibits NF-κB Redundancy
Montecino-Rodriguez, Encarnacion
Dorshkind, Kenneth
JOURNAL OF IMMUNOLOGY, 2011, 187 (11): : 5712 - 5719
[8] B-1 CELLS ARE MADE, NOT BORN
HAUGHTON, G
ARNOLD, LW
WHITMORE, AC
CLARKE, SH
IMMUNOLOGY TODAY, 1993, 14 (02): : 84 - 87
[9] B-1 cells as a source of IgA
Meyer-Bahlburg, Almut
B-1 CELL DEVELOPMENT AND FUNCTION, 2015, 1362 : 122 - 131
[10] B-1 cells and the intestinal microflora
Bos, NA
Cebra, JJ
Kroese, FGM
B 1 LYMPHOCYTES IN B CELL NEOPLASIA, 2000, 252 : 211 - 220

← 1 2 3 4 5 →