Next generation platforms for high-throughput biodosimetry

被引：18

作者：

Repin, Mikhail ^{[1
]}

Turner, Helen C. ^{[1
]}

Garty, Guy ^{[1
]}

Brenner, David J. ^{[1
]}

机构：

[1] Columbia Univ, Med Ctr, Ctr High Throughput Minimally Invas Radiat Biodos, New York, NY 10032 USA

来源：

RADIATION PROTECTION DOSIMETRY | 2014年 / 159卷 / 1-4期

基金：

美国国家卫生研究院;

关键词：

IN-SITU HYBRIDIZATION; FLUORESCENCE INSITU HYBRIDIZATION; PERIPHERAL-BLOOD; CHROMOSOME-ABERRATIONS; MICRONUCLEUS ASSAY; FISH; RADIATION; EXPOSURE; LYMPHOCYTES; SYSTEM;

D O I：

10.1093/rpd/ncu161

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Here the general concept of the combined use of plates and tubes in racks compatible with the American National Standards Institute/the Society for Laboratory Automation and Screening microplate formats as the next generation platforms for increasing the throughput of biodosimetry assays was described. These platforms can be used at different stages of biodosimetry assays starting from blood collection into microtubes organised in standardised racks and ending with the cytogenetic analysis of samples in standardised multiwell and multichannel plates. Robotically friendly platforms can be used for different biodosimetry assays in minimally equipped laboratories and on cost-effective automated universal biotech systems.

引用

页码：105 / 110

页数：6

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