Association of Sleep Duration, Midday Napping with Atrial Fibrillation in Patients with Hypertension

Objective: This study aimed to assess the associations of sleep duration, midday napping and the risk of atrial fibrillation (AF) in patients with hypertension. Methods: We conducted a cross-sectional study enrolling 11,524 hypertensive participates from the Chinese Hypertension Registry Study. Information on sleep duration and midday napping were obtained by a self-administered questionnaire. Multivariate logistic regression analyses were performed to estimate odds ratio (OR) and 95% confidence intervals (CIs) for the risk of AF. Results: Compared with sleeping 6 to <8 hours/night, those reporting shorter sleep duration (<5 hours/night) had a greater risk of AF (OR 1.95; 95% CI 1.28-2.95) in the fully adjusted model, while longer sleep (>= 9 hours/night) was not significantly associated with the risk of AF. Compared with nonhabitual nappers, nappers had a higher risk of AF (OR 1.28; 95% CI 1.03-1.60) in the fully adjusted model. Moreover, we observed significant joint effects of sleeping <5 hours/night and nap (OR 2.13; 95% CI 1.09-4.14) on the risk of AF after adjusting for confounding factors. Conclusion: Short sleep duration and midday napping were independently and jointly associated with higher risks of AF in patients with hypertension.