Acute myeloid leukaemia with t(8;16)(p11;p13) in a child after intrauterine X-ray exposure

被引：10

作者：

Savasan, S

Mohamed, AN

Lucas, DR

Dugan, MC

Ryan, JR

Ravindranath, Y

机构：

[1] HARPER GRACE HOSP, DEPT PATHOL, DETROIT, MI USA

[2] HUTZEL HOSP, DEPT PATHOL, DETROIT, MI USA

[3] CHILDRENS HOSP MICHIGAN, DEPT PATHOL, DETROIT, MI USA

[4] HUTZEL HOSP, DEPT ORTHOPED, DETROIT, MI USA

来源：

BRITISH JOURNAL OF HAEMATOLOGY | 1996年 / 94卷 / 04期

关键词：

t(8; 16); AML-M4; prenatal X-ray exposure;

D O I：

10.1046/j.1365-2141.1996.02345.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We describe t(8;16)(p11:p13) acute myeloid leukaemia (AML-M4) in a 12-year-old white male with a history of prenatal X-ray exposure, He had skin and bone involvement and some of the leukaemic blasts showed haemophagocytosis, characteristic features seen in (8;16) AML. 20% of the reported cases of t(8:16)(p11,p13) AML are therapy-related and this case further supports the possible role of the ionizing radiation in the development of this disorder.

引用

页码：702 / 704

页数：3

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