Antitumor activity of β-D-glucan from Libyan dates

被引:23
|
作者
Ishurd, O [1 ]
Zgheel, F
Kermagi, A
Flefla, M
Elmabruk, M
机构
[1] Zhejiang Univ, Dept Chem, Hangzhou 310027, Peoples R China
[2] Biotechnol Res Ctr, Tripoli, Libya
关键词
dates; D-glucan; polysaccharides;
D O I
10.1089/1096620041224085
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
beta-Glucan with antitumor activities was isolated from Libyan dates, and the structure of the purified glucan was characterized using methods such as methylation, periodate oxidation, and acetolysis. Glucans were found to exhibit potent antitumor activity; this activity could be correlated to their (1 --> 3)-beta-D-glucan linkages. Such antitumor glucans have also been obtained from a number of other sources, such as yeast, fungi, bacteria, and plants. This is the first study to report antitumor activity for date glucan.
引用
收藏
页码:252 / 255
页数:4
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