Cognitive Neuropsychology of HIV-Associated Neurocognitive Disorders

被引：417
|
作者：
Woods, Steven Paul [1 ,2 ]
Moore, David J. [2 ]
Weber, Erica [2 ]
Grant, Igor [2 ]
机构：
[1] Univ Calif San Diego, Dept Psychiat 0847, HIV Neurobehav Res Ctr, San Diego, CA 92103 USA
[2] Univ Calif San Diego, Sch Med, Dept Psychiat 0847, La Jolla, CA 92093 USA
来源：
NEUROPSYCHOLOGY REVIEW | 2009年 / 19卷 / 02期
基金：
美国国家卫生研究院;
关键词：
Human immunodeficiency virus; AIDS dementia complex; Neuropsychological assessment; Cognitive science; Cognitive impairment; HUMAN-IMMUNODEFICIENCY-VIRUS; AIDS DEMENTIA COMPLEX; ACTIVE ANTIRETROVIRAL THERAPY; SUBSTANCE-DEPENDENT INDIVIDUALS; WORKING-MEMORY PERFORMANCE; VERBAL-LEARNING TEST; QUALITY-OF-LIFE; BRAIN-INJURY; INFECTED INDIVIDUALS; MEDICATION ADHERENCE;
D O I：
10.1007/s11065-009-9102-5
中图分类号：
B849 [应用心理学];
学科分类号：
040203 ;
摘要：
Advances in the treatment of the human immunodeficiency virus (HIV) have dramatically improved survival rates over the past 10 years, but HIV-associated neurocognitive disorders (HAND) remain highly prevalent and continue to represent a significant public health problem. This review provides an update on the nature, extent, and diagnosis of HAND. Particular emphasis is placed on critically evaluating research within the realm of cognitive neuropsychology that aims to elucidate the component processes of HAND across the domains of executive functions, motor skills, speeded information processing, episodic memory, attention/working memory, language, and visuoperception. In addition to clarifying the cognitive mechanisms of HAND (e.g., impaired cognitive control), the cognitive neuropsychology approach may enhance the ecological validity of neuroAIDS research and inform the development of much needed novel, targeted cognitive and behavioral therapies.
引用
收藏
页码：152 / 168
页数：17
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