Angiotensin-converting enzyme and heart chymase gene polymorphisms in hypertrophic cardiomyopathy

被引：55

作者：

Pfeufer, A

Osterziel, K

Urata, H

Borck, G

Schuster, H

Wienker, T

Dietz, R

Luft, FC

机构：

[1] FRANZ VOLHARD CLIN,D-13122 BERLIN,GERMANY

[2] HUMBOLDT UNIV BERLIN,KLINIKUM RUDOLF VIRCHOW,MAX DELBRUCK CTR MOLEC MED,BERLIN,GERMANY

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 1996年 / 78卷 / 03期

关键词：

D O I：

10.1016/S0002-9149(96)00296-2

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We examined the insertion/deletion polymorphism in the angiotensin- converting enzyme gene and identified polymorphisms in the heart chymase gene to test the hypothesis that these angiotensin II-producing enzymes are associated with a monogenic cardiac disease (50 patients and 50 control subjects) as a model of cardiac hypertrophy. We found that the angiotensin- converting enzyme DD genotype was present more often in patients than in control subjects and identified a possible interaction with 1 of the chymase polymorphisms.

引用

页码：362 / 364

页数：3

共 50 条

[1] The Influence of Angiotensin Converting Enzyme and Angiotensinogen Gene Polymorphisms on Hypertrophic Cardiomyopathy
Luo, Rong
Li, Xiaoping
Wang, Yuequn
Li, Yongqing
Deng, Yun
Wan, Yongqi
Jiang, Zhigang
Hua, Wei
Wu, Xiushan
PLOS ONE, 2013, 8 (10):
[2] ANGIOTENSIN-CONVERTING ENZYME GENE POLYMORPHISM IN JAPANESE PATIENTS WITH HYPERTROPHIC CARDIOMYOPATHY
YONEYA, K
OKAMOTO, H
MACHIDA, M
ONOZUKA, H
NOGUCHI, M
MIKAMI, T
KAWAGUCHI, H
MURAKAMI, M
UEDE, T
KITABATAKE, A
AMERICAN HEART JOURNAL, 1995, 130 (05) : 1089 - 1093
[3] Angiotensin-converting enzyme gene polymorphisms
Malik, FS
Lavie, CJ
AMERICAN HEART JOURNAL, 1998, 136 (03) : 562 - 563
[4] Influence of angiotensin-converting enzyme and angiotensinogen gene polymorphisms in the phenotypic expression of Spanish patients with hypertrophic cardiomyopathy
López-Haldón, J
García-Lozano, JR
Martínez, AM
Núñez-Roldán, A
Cornejo, JB
MEDICINA CLINICA, 1999, 113 (05): : 161 - 163
[5] Association of angiotensin-converting enzyme polymorphism with phenotype of hypertrophic cardiomyopathy
Freitas Pereira Gondar, A.
Sales, A. L. F.
Gil, T. C. P.
Bittencourt, M. I.
Castier, M. B.
Da Silva, D. A.
Mourilhe-Rocha, R.
EUROPEAN JOURNAL OF HEART FAILURE, 2016, 18 : 133 - 134
[6] Progression of left ventricular hypertrophy and the angiotensin-converting enzyme gene polymorphism in hypertrophic cardiomyopathy
Doolan, G
Nguyen, L
Chung, J
Ingles, J
Semsarian, C
INTERNATIONAL JOURNAL OF CARDIOLOGY, 2004, 96 (02) : 157 - 163
[7] Effects of angiotensin-converting enzyme inhibitor on angiotensin converting enzyme and chymase gene transcript levels in heart, lung, and kidney in a canine model of heart failure
Su, XF
Schultz, D
DellItalia, LJ
CIRCULATION, 1997, 96 (08) : 828 - 828
[8] Polymorphisms of angiotensin-converting enzyme 2 gene associated with magnitude of left ventricular hypertrophy in male patients with hypertrophic cardiomyopathy
Shu-Xia, Wang
Chun-Yan, Fu
Yu-Bao, Zou
Hu, Wang
Yi, Shi
Xi-Qi, Xu
Jing-Zhou, Chen
Xiao-Dong, Song
Tu-Jun, Huan
Ru-Tai, Hui
CHINESE MEDICAL JOURNAL, 2008, 121 (01) : 27 - 31
[9] Polymorphisms of angiotensin-converting enzyme 2 gene associated with magnitude of left ventricular hypertrophy in male patients with hypertrophic cardiomyopathy
WANG Shuxia FU Chunyan ZOU Yubao WANG Hu SHI Yi XU Xiqi CHEN Jingzhou SONG Xiaodong HUAN Tujun and HUI Rutai Department of CardiologyFuwai Hospital and Cardiovascular InstituteChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing China SinoGerman Laboratory for Molecular MedicineKey Laboratory for Clinical Cardiovascular Genetics of Ministry of EducationBeijing China
中华医学杂志(英文版), 2008, (01) : 27 - 31
[10] Effects of astragalus polysaccharides on chymase, angiotensin-converting enzyme and angiotensin II in diabetic cardiomyopathy in hamsters
Chen, Wei
Li, Yi-Ming
Yu, Mao-Hua
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH, 2007, 35 (06) : 873 - 877

← 1 2 3 4 5 →