Cardiac arrest following chloroquine overdose treated with bicarbonate and lipid emulsion

被引：0

作者：

Bethlehem, C. ^{[1
,3
]}

Jongsma, M. ^{[2
]}

Korporaal-Heijman, J. ^{[2
]}

Yska, J. P. ^{[3
]}

机构：

[1] ZGT Hosp, Dept Intens Care, Almelo, Netherlands

[2] Tjongerschans Hosp, Dept Clin Pharm, Heerenveen, Netherlands

[3] Med Ctr Leeuwarden, Dept Clin Pharm & Clin Pharmacol, Leeuwarden, Netherlands

来源：

NETHERLANDS JOURNAL OF MEDICINE | 2019年 / 77卷 / 05期

关键词：

Chloroquine; poisoning; intravenous lipid emulsion; intraosseous; alkalinisation; sodium bicarbonate; diazepam;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We describe a 27-year-old female with repeated episodes of pulseless electrical activity due to intoxication with a substance that was unidentified at presentation. Severe QRS widening was observed and empiric treatment with sodium bicarbonate and intravenous lipid emulsion was administered. In this case, intraosseous administration of lipid emulsion failed to improve haemodynamic parameters, suggesting that this dose remained in the bone marrow compartment. We recommend that physicians become aware of this possibility and to avoid intraosseous administration of lipid emulsion.

引用

页码：186 / 188

页数：3

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