Evidence that the dominant follicle of the first wave is more active than that of the second wave in terms of its growth rate, blood flow supply and steroidogenic capacity in cows

被引：20

作者：

Miura, Ryotaro ^{[1
,2
]}

Haneda, Shingo ^{[2
]}

Lee, Hsu-Hsun ^{[1
,2
]}

Miyamoto, Akio ^{[3
]}

Shimizu, Takashi ^{[3
]}

Miyahara, Kazuro ^{[2
]}

Miyake, Yoh-Ichi ^{[2
]}

Matsui, Motozumi ^{[2
]}

机构：

[1] Gifu Univ, United Grad Sch Vet Sci, Gifu 5011193, Japan

[2] Obihiro Univ Agr & Vet Med, Dept Vet Clin Sci, Obihiro, Hokkaido 0808555, Japan

[3] Obihiro Univ Agr & Vet Med, Grad Sch Anim & Food Hyg, Obihiro, Hokkaido 0808555, Japan

来源：

ANIMAL REPRODUCTION SCIENCE | 2014年 / 145卷 / 3-4期

基金：

日本学术振兴会;

关键词：

Cow; Follicular wave; Follicular growth; Blood flow; Granulosa cells; BOVINE PREOVULATORY FOLLICLES; LUTEINIZING-HORMONE; GENE-EXPRESSION; CORPUS-LUTEUM; NITRIC-OXIDE; OVULATORY FOLLICLE; OVARIAN; CATTLE; PROGESTERONE; HEIFERS;

D O I：

10.1016/j.anireprosci.2014.01.003

中图分类号：

S8 [畜牧、动物医学、狩猎、蚕、蜂];

学科分类号：

0905 ;

摘要：

To clarify the wave (DF-1) after spontaneous ovulation and DF in second follicular wave (DF-2) and after induced ovulation of the first-wave DF by GnRH were examined in non-lactating Holstein cows. Follicular maturation of DF-1 and DF-2 were induced by PGF2 alpha and GnRH treatment on Day 6 and 8 (Day 0 = Day of follicular wave emergence), respectively. Follicular growth and blood flow (BF) in the follicular wall of DF-1 and DF-2 were examined. To analyze sex steroids in follicular fluid (FF) and amount of mRNA in granulosa cells, DF-1 and DF-2 were aspirated on Day 8 or 9 in different estrous cycle. Diameter in DF-1 was larger than DF-2 on Day 8 and 9. From Day 8 to 9, BF area (BFA) and percentage of the follicular wall with BF, which represents the degree of distribution of BF, increased in DF-1 but not in DF-2. BFA per length of follicle circumference with BF, which represents the thickness of BF, was not different between DF-1 and DF-2. Concentrations of 17 beta-estradiol (E2) in plasma, E2 and androstendione in FF and amounts of LH receptor mRNA were greater in the DF-1 on Day 8. Gene expression for steroidogenesis, prostaglandin synthesis and angiogenesis did not differ between DF-1 and DF-2. These results indicated that DF-1 were more active than DF-2 in growth, BF supply and steroidogenesis. The greater BFA observed in the DF-1 may be derived from as a result of the greater vascularity in the follicular wall. (C) 2014 Elsevier B.V. All rights reserved.

引用

页码：114 / 122

页数：9

共 2 条

[1] Differences of follicular growth and blood flow in the follicular wall between the first and second wave dominant follicles in cows
Miura, R.
Matsui, M.
Haneda, S.
Miyake, Y-I
REPRODUCTION IN DOMESTIC RUMINANTS VII, 2010, 67 : 559 - 559
[2] The role of Insulin-like Growth Factor 1 (IGF-1) in development of an estrogen-active dominant follicle during the first follicular wave postpartum in dairy cows
Kawashima, C.
Sudo, N.
Montoya, C. Amaya
Kaneko, E.
Matsui, M.
Matsunaga, N.
Tetsuka, M.
Shimizu, T.
Kida, K.
Miyake, Y. -I.
Miyamoto, A.
REPRODUCTION FERTILITY AND DEVELOPMENT, 2007, 19 (01) : 242 - 243

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