Temporal lobe epilepsy surgical outcome prediction

被引:0
|
作者
Duchesne, S [1 ]
Bernasconi, N [1 ]
Bernasconi, A [1 ]
Collins, DL [1 ]
机构
[1] McGill Univ, Montreal Neurol Inst, Montreal, PQ H3A 2B4, Canada
关键词
temporal lobe epilepsy; surgical outcome; voxel-based morphometry; grey matter atrophy; white matter atrophy; linear discriminant analysis;
D O I
暂无
中图分类号
TP39 [计算机的应用];
学科分类号
081203 ; 0835 ;
摘要
We wished to study pre-operative T1-weighted MRI of intractable temporal lobe epilepsy (TLE) patients who had undergone selective amygdala-hippocampectomy as part of their surgical treatment. We performed a voxel-based morphometry study of gray and white matter (CM,WM) concentration changes by comparing TLE patients with positive and negative surgical outcome. GM concentration changes were primarily located in the left lateral temporal neocortical region, while more extensive changes were found in left lateral temporal and occipital WM. Using those areas to define a region of interest, we showed that mean GM and WM concentration for all voxels within that region can be used to predict surgical outcome with 97% accuracy.
引用
收藏
页码:696 / 702
页数:7
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