Triple-negative breast cancers - a panoply of cancer types

被引：45
|
作者：
Pareja, Fresia [1 ]
Reis-Filho, Jorge S. [1 ]
机构：
[1] Mem Sloan Kettering Canc Ctr, Dept Pathol, 1275 York Ave, New York, NY 10021 USA
来源：
NATURE REVIEWS CLINICAL ONCOLOGY | 2018年 / 15卷 / 06期
关键词：
SUBTYPES;
D O I：
10.1038/s41571-018-0001-7
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
The biological complexity of triple-negative breast cancers (TNBCs) and the lack of highly recurrent targetable genetic alterations pose major challenges for the implementation of targeted therapies for this disease. A recent multiomic in silico study has identified genetic drivers of five different TNBC molecular subtypes, providing new opportunities for precision medicine approaches.
引用
收藏
页码：347 / 348
页数：2
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