Complete remission of pulmonary spindle cell carcinoma after treatment with oral germanium sesquioxide

被引:28
|
作者
Mainwaring, MG
Poor, C
Zander, DS
Harman, E
机构
[1] Univ Florida, Coll Med, Dept Med, Div Hematol & Oncol, Gainesville, FL 32610 USA
[2] Univ Florida, Coll Med, Dept Med, Div Pulm Med, Gainesville, FL 32610 USA
[3] Univ Florida, Coll Med, Dept Pathol Immunol & Lab Med, Gainesville, FL 32610 USA
[4] Vet Affairs Med Ctr, Gainesville, FL 32608 USA
关键词
germanium sesquioxide; spindle cell carcinoma;
D O I
10.1378/chest.117.2.591
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Spindle cell carcinoma (SCC) is a rare form of lung cancer representing 0.2 to 0.3% of all primary pulmonary malignancies. Even with combined surgery, chemotherapy, and radiation therapy, these tumors are associated with a poor prognosis and only 10% of patients survive 2 veers after diagnosis. We describe a patient with an unresectable SCC who, following no response to conventional treatment with combined modality therapy, chose to medicate herself with daily doses of germanium obtained in a health food stole. She noted prompt symptomatic improvement and remains clinically and radiographically fr ee of disease tl 2 months after starting her alternative therapy.
引用
收藏
页码:591 / 593
页数:9
相关论文
共 50 条
  • [1] Complete remission of locally advanced penile squamous cell carcinoma after multimodality treatment
    Meng, Yifan
    Bernie, Helen Levey
    Weng, Tzu-Hua
    Ling, Dean-An
    Messing, Edward M.
    Guancial, Elizabeth
    RARE TUMORS, 2016, 8 (04) : 191 - 193
  • [2] Complete Remission of Basal Cell Carcinoma Following Treatment With Cemiplimab After 2 Years
    Dumann, Konstantin
    Artz, Niklas
    Ziemer, Mirjana
    JAMA DERMATOLOGY, 2021, 157 (08) : 1004 - 1006
  • [3] Complete remission of pulmonary metastasized renal cell carcinoma after inhalative interleukin-2 therapy
    Rohrmann, K
    Schleypen, J
    Adam, C
    Hofstetter, A
    Siebels, M
    UROLOGE A, 2004, 43 (10): : 1271 - 1274
  • [4] Merkel cell carcinoma Metastases: Complete remission after intratumoral treatment with Interleukin-2
    Andonov, E.
    Eigentler, T.
    Leiter, U.
    Garbe, C.
    JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, 2011, 9 : 232 - 232
  • [5] LANGERHANS CELL HISTIOCYTOSIS - COMPLETE REMISSION AFTER ORAL ISOTRETINOIN THERAPY
    TSAMBAOS, D
    GEORGIOU, S
    KAPRANOS, N
    MONASTIRLI, A
    STRATIGOS, A
    BERGER, H
    ACTA DERMATO-VENEREOLOGICA, 1995, 75 (01) : 62 - 64
  • [6] Complete remission of combined pulmonary large cell neuroendocrine carcinoma: a case report
    Xu, Jian
    Feng, Qi
    Chen, Yong
    Liu, Xiu-lan
    Jiang, Ou
    JOURNAL OF INTERNATIONAL MEDICAL RESEARCH, 2021, 49 (11)
  • [7] COMPLETE REMISSION AFTER MULTIPLE-DRUG CHEMOTHERAPY OF LARGE CELL PULMONARY-CARCINOMA - DESCRIPTION OF A CASE
    SPAGHI, A
    COSTA, D
    GANGAROSSA, I
    CASTOLDI, O
    PASOTTI, D
    ALBERGATI, MG
    NASTASI, G
    MEDICINA-RIVISTA DELLA ENCICLOPEDIA MEDICA ITALIANA, 1989, 9 (01): : 54 - 56
  • [8] Complete remission of Merkel cell carcinoma of the scalp with local and regional metastases after topical treatment with dinitrochlorbenzol
    Herrmann, G
    Groth, W
    Krieg, T
    Mauch, C
    JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2004, 50 (06) : 965 - 969
  • [9] Complete Remission of Squamous Cell Carcinoma After Treatment With Panitumumab in a Patient With Cetuximab-Induced Anaphylaxis
    Marti, Aurelie
    Fauconneau, Antoine
    Ouhabrache, Nora
    Beylot-Barry, Marie
    Pham-Ledard, Anne
    JAMA DERMATOLOGY, 2016, 152 (03) : 343 - 345
  • [10] Sarcomatoid changes of pulmonary squamous cell carcinoma to pulmonary spindle cell carcinoma
    Tono, Katsuharu
    Sibata, Masaru
    Ohashi, Hiroshi
    Moriyama, Yasuhiro
    ANNALS OF ONCOLOGY, 2022, 33 : S525 - S525