Studying Cooperative Ligand Binding in the Undergraduate Biochemistry Laboratory: Oxygen-Hemoglobin Dissociation Revisited

被引：0

作者：

Young, Megan K. M. ^{[1
]}

Gries, Theodore J. ^{[1
]}

机构：

[1] Beloit Coll, Dept Chem, Beloit, WI 53511 USA

来源：

JOURNAL OF CHEMICAL EDUCATION | 2015年 / 92卷 / 12期

关键词：

Upper-Division Undergraduate; Biochemistry; Laboratory Instruction; Inquiry-Based/Discovery Learning; Biophysical Chemistry; Conformational Analysis; Laboratory Equipment/Apparatus; Proteins/Peptides;

D O I：

10.1021/acs.jchemed.5b00374

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The interaction between oxygen and hemoglobin is a classic example of a cooperative ligand-binding process. This gaseous-ligand binding process may be studied in the undergraduate laboratory with a variable-pressure cuvette apparatus. An updated method is described to assemble a variable-pressure cuvette apparatus composed of inexpensive supplies and equipment commonly found in the chemistry laboratory.

引用

页码：2173 / 2175

页数：3

共 50 条

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