Irradiating single cells using Cracow microprobe facility

被引：13
|
作者：
Polak, W.
Veselov, O.
Lekki, J.
Stachura, Z.
Zazula, M.
Ugenskiene, R.
Polak, M.
Styczen, J.
机构：
[1] Polish Acad Sci, Henryk Niewodniczanski Inst Nucl Phys, PL-31342 Krakow, Poland
[2] Jagiellonian Univ, Coll Med, PL-30059 Krakow, Poland
[3] Queen Alexandra Hosp, TORC Labd, Portsmouth PO6 3LY, Hants, England
来源：
NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS | 2006年 / 249卷
关键词：
ion microprobe; single hit facility; cells irradiation;
D O I：
10.1016/j.nimb.2006.03.131
中图分类号：
TH7 [仪器、仪表];
学科分类号：
0804 ; 080401 ; 081102 ;
摘要：
The Cracow single ion hit facility (SIH) is using the Van de Graaff-based microprobe with current spatial resolution of about 10 mu m in vacuum. Living cells are irradiated with the exact number of 2 MeV protons. This work shows the present setup and test measurements optimizing the detection of single protons, beam deflection after registering single proton and the accuracy of cell targeting as well as the description of performance of the whole setup. The article presents also ways of cells visualisation and positioning during a single measurement and reports on first experiments with living cells carried out at the new facility. (c) 2006 Elsevier B.V. All rights reserved.
引用
收藏
页码：743 / 746
页数：4
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