Proteolytic degradation of the recombinant target protein, interferon-τ during its fermentative production in the methylotrophic yeast, Pichia pastoris.

被引:0
|
作者
Sinha, J
Plantz, B
Schlegel, V
Zeece, M
Villarete, LH
Meagher, MM
机构
[1] Univ Nebraska, Dept Chem Engn, Biol Proc Dev Facil, Lincoln, NE 68583 USA
[2] Univ Nebraska, Dept Food Sci & Technol, Biol Proc Dev Facil, Lincoln, NE USA
[3] Univ Nebraska, Dept Food Sci & Technol, Lincoln, NE 68583 USA
关键词
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
094-BIOT
引用
收藏
页码:U214 / U214
页数:1
相关论文
共 50 条
  • [1] Causes of proteolytic degradation of secreted recombinant proteins produced in methylotrophic yeast Pichia pastoris:: Case study with recombinant ovine interferon-τ
    Sinha, J
    Plantz, BA
    Inan, M
    Meagher, MM
    BIOTECHNOLOGY AND BIOENGINEERING, 2005, 89 (01) : 102 - 112
  • [2] Production of the recombinant human fibroblast interferon in Pichia pastoris.
    Parfenova, L
    Padkina, MV
    YEAST, 2003, 20 : S313 - S313
  • [3] The proteolytic systems and heterologous proteins degradation in the methylotrophic yeast Pichia pastoris
    Zhang, Yewang
    Liu, Ruijiang
    Wu, Xiaoyu
    ANNALS OF MICROBIOLOGY, 2007, 57 (04) : 553 - 560
  • [4] Expression and characterization of human interferon-β I in the methylotrophic yeast Pichia pastoris
    Skoko, N
    Argamante, B
    Kovacevic, N
    Grujicic, NK
    Tisminetzky, SG
    Glisin, V
    Ljubijankic, G
    BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY, 2003, 38 : 257 - 265
  • [5] Expression of recombinant human protein disulfide isomerase in the yeast Pichia pastoris.
    Hoffmann, K
    Onodera, S
    Noiva, R
    FASEB JOURNAL, 1996, 10 (06): : 677 - 677
  • [6] Recombinant production of bacterial toxins and their derivatives in the methylotrophic yeast Pichia pastoris
    Gurkan, C
    Ellar, DJ
    MICROBIAL CELL FACTORIES, 2005, 4 (1) : 1 - 8
  • [7] Production and purification of recombinant hirudin expressed in the methylotrophic yeast Pichia pastoris
    Rosenfeld, SA
    Nadeau, D
    Tirado, J
    Hollis, GF
    Knabb, RM
    Jia, S
    PROTEIN EXPRESSION AND PURIFICATION, 1996, 8 (04) : 476 - 482
  • [8] Recombinant production of bacterial toxins and their derivatives in the methylotrophic yeast Pichia pastoris
    Cemal Gurkan
    David J Ellar
    Microbial Cell Factories, 4
  • [9] Fermentation strategies for recombinant protein expression in the methylotrophic yeast Pichia pastoris
    Zhang W.
    Inan M.
    Meagher M.M.
    Biotechnology and Bioprocess Engineering, 2000, 5 (4) : 275 - 287
  • [10] Production of a recombinant bovine enterokinase catalytic subunit in the methylotrophic yeast Pichia pastoris
    Vozza, LA
    Wittwer, L
    Higgins, DR
    Purcell, TJ
    Bergseid, M
    CollinsRacie, LA
    LaVallie, ER
    Hoeffler, JP
    BIO-TECHNOLOGY, 1996, 14 (01): : 77 - 81