A novel method for sequence independent incorporation of activated/protected cysteine in Fmoc solid phase peptide synthesis

被引：16
|
作者：
Ghosh, AK
Fan, E
机构：
[1] Univ Washington, Dept Biol Struct, Seattle, WA 98195 USA
[2] Univ Washington, Biomol Struct Ctr, Seattle, WA 98195 USA
来源：
TETRAHEDRON LETTERS | 2000年 / 41卷 / 02期
关键词：
D O I：
10.1016/S0040-4039(99)02045-6
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
In conventional stepwise Fmoc solid phase peptide synthesis, incorporation of cysteine with nitro-pyridine sulfenyl (Npys) or pyridine sulfenyl (Pys) groups which act as an activation/protection of the thiol function has been accomplished in a sequence independent manner. (C) 1999 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：165 / 168
页数：4
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