Micronutrient status assessment in humans: Current methods of analysis and future trends

被引：20

作者：

Holler, Ulrich ^{[1
,2
]}

Bakker, Stephan J. L. ^{[3
]}

Dusterloh, Andre ^{[1
,2
]}

Frei, Balz ^{[4
]}

Koehrle, Josef ^{[5
]}

Konz, Tobias ^{[6
]}

Lietz, Georg ^{[7
]}

McCann, Adrian ^{[8
,15
]}

Michels, Alexander J. ^{[4
]}

Molloy, Anne M. ^{[9
]}

Murakami, Hitoshi ^{[10
]}

Rein, Dietrich ^{[16
]}

Saris, Wim H. M. ^{[11
]}

Schmidt, Karlheinz ^{[12
]}

Shimbo, Kazutaka ^{[10
]}

Schumacher, Soeren ^{[13
]}

Vermeer, Cees ^{[14
]}

Kaput, Jim ^{[6
,17
]}

Weber, Peter ^{[1
,2
]}

Eggersdorfer, Manfred ^{[1
,2
]}

Rezzi, Serge ^{[6
]}

机构：

[1] DSM Nutr Prod Res & Dev, Analyt Res Ctr, Kaiseraugst, Switzerland

[2] DSM Nutr Prod Res & Dev, Nutr Sci & Advocacy, Kaiseraugst, Switzerland

[3] Univ Groningen, Univ Med Ctr Groningen, Groningen, Netherlands

[4] Oregon State Univ, Linus Pauling Inst, Corvallis, OR 97331 USA

[5] Charite, Berlin, Germany

[6] Nestle Inst Hlth Sci, Lausanne, Switzerland

[7] Newcastle Univ, Newcastle Upon Tyne, Tyne & Wear, England

[8] Univ Ulster, Coleraine, Londonderry, North Ireland

[9] Trinity Coll Dublin, Sch Med, Dublin, Ireland

[10] Ajinomoto Co Inc, Tokyo, Japan

[11] Maastricht Univ Med Ctr, NUTRIM Sch Nutr & Translat Res Metab, Dept Human Biol, Maastricht, Netherlands

[12] Univ Tubingen, Tubingen, Germany

[13] Fraunhofer Inst Biomed Engn, Potsdam, Germany

[14] Maastricht Univ, VitaK, Maastricht, Netherlands

[15] Bevital AS, Bergen, Norway

[16] BASF SE, Lampertheim, Germany

[17] Vydiant Inc, Gold River, CA USA

来源：

TRAC-TRENDS IN ANALYTICAL CHEMISTRY | 2018年 / 102卷

关键词：

Analytical methodology; Fat-soluble vitamins; Human nutrition; Marker for micronutrient status; Micronutrient status assessment; Minerals; Trace elements; Water-soluble vitamins; PERFORMANCE LIQUID-CHROMATOGRAPHY; STABLE-ISOTOPE DILUTION; VITAMIN-D METABOLITES; HUMAN PLASMA; LC-MS/MS; WHOLE-BLOOD; MASS-SPECTROMETRY; ALPHA-TOCOPHEROL; PANTOTHENIC-ACID; SOLUBLE VITAMINS;

D O I：

10.1016/j.trac.2018.02.001

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Micronutrients are essential to health at every life stage and their deficiencies are associated with increased incidence of various pathophysiological states and poor quality of life. Efficient methods are therefore needed to monitor micronutrient status of individuals and to improve evidenced-based recommendations for populations. This review (i) reports current approaches to assess the vitamin and mineral status in humans, (ii) summarizes current analytical advantages and shortcomings and (iii) provides practical information for both nutrition research and nutritional status diagnostics. Future analytical perspectives are discussed in relation to micronutrient profiling, analytical sensitivity, and miniaturized technologies. (C) 2018 Elsevier B.V. All rights reserved.

引用

页码：110 / 122

页数：13

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