Male germ cell specification and differentiation

被引:105
|
作者
Zhao, GQ
Garbers, DL [1 ]
机构
[1] Univ Texas, SW Med Sch, Cecil H & Ida Green Ctr Reprod Biol Sci, Dallas, TX 75390 USA
[2] Univ Texas, SW Med Sch, Howard Hughes Med Inst, Dallas, TX 75390 USA
[3] Univ Texas, SW Med Sch, Dept Pharmacol, Dallas, TX 75390 USA
关键词
D O I
10.1016/S1534-5807(02)00173-9
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Understanding the mechanisms by which the germline is induced and maintained should lead to a broader understanding of the means by which pluripotency is acquired and maintained. In this review, two major aspects of male germ cell development are discussed: underlying mechanisms for induction and maintenance of primordial germ cells and the basic signaling pathways that determine spermatogonial cell fate.
引用
收藏
页码:537 / 547
页数:11
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