Background: Wilms tumor (WT) is the second most common abdominal tumor in children. Methods: This chapter discusses surgical considerations for the management of unilateral and bilateral WT. Results: Currently, survival exceeds 90%, owing to multicenter studies under the auspices of the Children's Oncology Group and Societe Internationale d'Oncologie Pediatrique. Surgical excision remains the mainstay of oncologic control and is also crucial for proper staging of disease in order to direct adjuvant therapy and limit treatment-related morbidity. Conclusions: Careful attention must be paid to proper disease staging, upfront and adjuvant therapy, and surgical technique in order to optimize oncologic outcomes while minimizing short- and long-term morbidity. (C) 2016 Elsevier Inc. All rights reserved.
机构:G Sonn is a Senior Urology Resident at Stanford University Medical Center,LMD Shortliffe is the Stanley McCormick Memorial Professor and Chair of the Department of Urology at Stanford University and Chief of Pediatric Urology at Lucile Salter Packard Child
Geoffrey Sonn
Linda MD Shortliffe
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机构:G Sonn is a Senior Urology Resident at Stanford University Medical Center,LMD Shortliffe is the Stanley McCormick Memorial Professor and Chair of the Department of Urology at Stanford University and Chief of Pediatric Urology at Lucile Salter Packard Child
Linda MD Shortliffe
Nature Clinical Practice Urology,
2008,
5
: 551
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560
机构:
Stanford Univ, Dept Urol, Stanford, CA 94305 USA
Lucile Salter Packard Childrens Hosp, Palo Alto, CA USAStanford Univ, Med Ctr, Stanford, CA 94305 USA
机构:
Univ Penn, Clin Studies New Bolton Ctr, Sch Vet Med, Kennett Sq, PA 19104 USAUniv Penn, Clin Studies New Bolton Ctr, Sch Vet Med, Kennett Sq, PA 19104 USA