ESBL-production in Escherichia coli and Klebsiella pneumoniae isolates from Nigeria

被引:10
|
作者
Hertz, Frederik B. [1 ,2 ]
Jansaker, Fillip [1 ]
Okon, Kenneth O. [3 ]
Abdulmumin, Ibrahim S. [6 ]
Onah, Joseph O. [4 ]
Ladan, Joshua [5 ]
Knudsen, Jenny D. [1 ]
机构
[1] Univ Copenhagen, Hvidovre Hosp, Dept Clin Microbiol, Hvidovre, Denmark
[2] Statens Serum Inst, Dept Virus & Microbiol Special Diagnost, Copenhagen, Denmark
[3] Fed Med Ctr, Dept Med Microbiol, Makurdi, Nigeria
[4] Clinton Hlth Access Initiat, Abuja, Nigeria
[5] Natl Primary Hlth Care Dev Agcy, Dept Dis & Immunizat, Abuja, Nigeria
[6] Abubakar Tafawa Balewa Univ Teaching Hosp, Dept Med Microbiol, Bauchi, Nigeria
来源
MICROBIOLOGYOPEN | 2019年 / 8卷 / 09期
关键词
Enterobacteriaceae; ESBL; Escherichia coli; Klebsiella pneumoniae; Nigeria;
D O I
10.1002/mbo3.816
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The worldwide increase in infections caused by extended-spectrum beta-lactamase- (ESBL) and AmpC-producing Enterobacteriaceae (ESBL-E) is a concern. Surveillance is extensive in Europe, North America, and Asia. Yet, there is no summarizing surveillance in Africa. This study aimed to perform a preliminary investigation on the prevalence of ESBL-E in the northeastern part of Nigeria. However, of the 60 samples collected, we were able to culture 15 Escherichia coli and 7 Klebsiella spp. only. In the collection of clinical hospital samples, we found eight of 15 E. coli isolates to be ESBL (53%) and two out of seven Klebsiella spp. to be ESBL/AmpC (29%). Due to the limitations of this study, our findings cannot take a broad view on the prevalence of ESBL-E, in Nigeria and other parts of Africa. Yet, to know which genes encode ESBL in Nigeria, and to know exact prevalence of every ESBL gene would be of importance.
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页数:3
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