Preparation, characterization and antibacterial effect of 2-methoxy-6-(5-H/Me/Cl/NO2-1H-benzimidazol-2-yl)phenols and some transition metal complexes

被引：26
|
作者：
Tavman, Aydin [1 ]
Ikiz, Serkan [2 ]
Bagcigil, A. Funda [2 ]
Ozgur, N. Yakut [2 ]
Ak, Seyyal [2 ]
机构：
[1] Istanbul Univ, Fac Engn, Dept Chem, TR-34320 Istanbul, Turkey
[2] Istanbul Univ, Fac Vet, Dept Microbiol, TR-34320 Istanbul, Turkey
来源：
JOURNAL OF THE SERBIAN CHEMICAL SOCIETY | 2009年 / 74卷 / 05期
关键词：
benzimidazolylphenols; complexes; antibacterial activity; ANTIMICROBIAL ACTIVITY; STRUCTURAL-CHARACTERIZATION; IRON(III) COMPLEXES; ZINC(II); LIGANDS; NICKEL(II); COBALT(II); ION;
D O I：
10.2298/JSC0905537T
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
2-Methoxy-6-(5-H/methyl/chloro/nitro-1H-benzimidazol-2-yl)phenols (HLx; x = 1-4, respectively) ligands and HL1 complexes with Fe(NO3)(3), Cu(NO3)(2), AgNO3 and Zn(NO3)(2) were synthesized and characterized. The structures of the compounds were confirmed based on elemental analysis, molar conductivity, magnetic moment, FT-IR, H-1- and C-13-NMR. The antibacterial activity and minimum inhibitory concentration (MIC) of the free ligands, their hydrochloride salts and the complexes were evaluated using the disk diffusion method in dimethyl sulfoxide (DMSO) and the dilution method, respectively, against 9 bacteria. HL1 and HL3, as well as the Cu(II) and Zn(II) complexes, showed antibacterial activity against Gram-positive bacteria.
引用
收藏
页码：537 / 548
页数：12
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