Seizure-Induced Increased 18F-DOPA Uptake in a Child With Diffuse Astrocytoma and Transient Brain MRI Abnormalities Related to Status Epilepticus

被引：5

作者：

Morana, Giovanni ^{[1
]}

Bottoni, Gianluca ^{[2
]}

Mancardi, Maria Margherita ^{[3
]}

Verrico, Antonio ^{[4
]}

Piccardo, Arnoldo ^{[2
]}

机构：

[1] Ist Giannina Gaslini, Neuroradiol Unit, Largo G Gaslini 5, I-16147 Genoa, Italy

[2] Osped Galliera, Dept Nucl Med, Genoa, Italy

[3] Ist Giannina Gaslini, Child Neuropsichiat Unit, Genoa, Italy

[4] Ist Giannina Gaslini, Neurooncol Unit, Genoa, Italy

来源：

CLINICAL NUCLEAR MEDICINE | 2018年 / 43卷 / 05期

关键词：

brain tumor; DOPA PET; glioma; pediatric; status epilepticus; MAGNETIC-RESONANCE; F-18-DOPA; PET;

D O I：

10.1097/RLU.0000000000002007

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

We report the finding of increased F-18-DOPA uptake in the brain parenchyma surrounding a temporoparietal low-grade diffuse astrocytoma and corresponding to transient seizure-induced MRI abnormalities. There was concomitant markedly increased tumoral uptake. This F-18-DOPA PET phenomenon may represent increased amino acid transport induced by seizures. In the setting of brain tumor imaging, increased F-18-DOPA uptake of low-grade epileptogenic tumors and adjacent brain parenchyma should be carefully interpreted in light of clinical and electroencephalographic findings related to seizure activity.

引用

页码：e149 / e150

页数：2

共 3 条

[1] Characteristics of Seizure-induced Reversible MRI Abnormalities in Status Epilepticus
Mariajoseph, Frederick
Sagar, Parveen
Muthusamy, Subramanian
Amukotuwa, Shalini
Seneviratne, Udaya
[J]. NEUROLOGY, 2022, 98 (18)
[2] Seizure-induced reversible MRI abnormalities in status epilepticus: A systematic review
Mariajoseph, Frederick P.
Sagar, Parveen
Muthusamy, Subramanian
Amukotuwa, Shalini
Seneviratne, Udaya
[J]. SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, 2021, 92 : 166 - 173
[3] Increased uptake of the P2X7 receptor radiotracer 18F-JNJ-64413739 in the brain and peripheral organs according to the severity of status epilepticus in male mice
Morgan, James
Moreno, Oscar
Alves, Mariana
Baz, Zurine
Mendez, Aida Menendez
Leister, Hanna
Melia, Ciara
Smith, Jonathon
Visekruna, Alexander
Nicke, Annette
Bhattacharya, Anindya
Ceusters, Marc
Henshall, David C.
Gomez-Vallejo, Vanessa
Llop, Jordi
Engel, Tobias
[J]. EPILEPSIA, 2023, 64 (02) : 511 - 523

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