Chromatin trapping is a key factor for anticancer cytotoxicity of DNA-binding small molecule drugs

被引：0
|
作者：
Nesher, Elimelech [1 ]
Safina, Alfiya [2 ]
Aljandali, Ieman [2 ]
Portwood, Scott [2 ]
Wang, Eunice [2 ]
Wang, Jianmin [2 ]
Koman, Igor [1 ]
Gurova, Katerina [2 ]
机构：
[1] Ariel Univ, Ariel, Israel
[2] Roswell Pk Comprehens Canc Ctr, Buffalo, NY USA
来源：
CANCER RESEARCH | 2019年 / 79卷 / 13期
关键词：
D O I：
10.1158/1538-7445.SABCS18-1755
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
1755
引用
收藏
页数：2
相关论文
共 50 条
  • [1] Role of Chromatin Damage and Chromatin Trapping of FACT in Mediating the Anticancer Cytotoxicity of DNA-Binding Small-Molecule Drugs
    Nesher, Elimelech
    Safina, Alfiya
    Aljahdali, Ieman
    Portwood, Scott
    Wang, Eunice S.
    Koman, Igor
    Wang, Jianmin
    Gurova, Katerina V.
    CANCER RESEARCH, 2018, 78 (06) : 1431 - 1443
  • [2] INFLUENCE OF DNA-BINDING DRUGS ON CHROMATIN CONDENSATION
    SEN, D
    CROTHERS, DM
    BIOCHEMISTRY, 1986, 25 (07) : 1503 - 1509
  • [3] DNA-Binding of ruthenium-arene anticancer drugs
    Gossens, Christian
    Tavemelli, Ivano
    Rothlisberger, Ursula
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2006, 232 : 396 - 396
  • [4] DNA-Binding Anticancer Drugs: One Target, Two Actions
    Baguley, Bruce C.
    Drummond, Catherine J.
    Chen, Ying Yi
    Finlay, Graeme J.
    MOLECULES, 2021, 26 (03):
  • [5] New hopes from old drugs: revisiting DNA-binding small molecules as anticancer agents
    Gurova, Katerina
    FUTURE ONCOLOGY, 2009, 5 (10) : 1685 - 1704
  • [6] Completion of a programmable DNA-binding small molecule library
    Hsu, Carey F.
    Phillips, John W.
    Trauger, John W.
    Farkas, Michelle E.
    Belitsky, Jason M.
    Heckel, Alexander
    Olenyuk, Bogdan Z.
    Puckett, James W.
    Wang, Clay C. C.
    Dervan, Peter B.
    TETRAHEDRON, 2007, 63 (27) : 6146 - 6151
  • [7] DNA-BINDING PROTEINS IN CHROMATIN STRUCTURE AND FUNCTION
    GILMOUR, RS
    LANG, A
    GU, JR
    JOHNSTON, C
    PAUL, J
    CELL BIOLOGY INTERNATIONAL REPORTS, 1981, 5 (01) : 45 - 53
  • [8] FACILITATED DIFFUSION OF A DNA-BINDING PROTEIN ON CHROMATIN
    HANNON, R
    RICHARDS, EG
    GOULD, HJ
    EMBO JOURNAL, 1986, 5 (12): : 3313 - 3319
  • [9] Echinomycin, a small-molecule inhibitor of hypoxia-inducible factor-1 DNA-binding activity
    Kong, DH
    Park, EJ
    Stephen, AG
    Calvani, M
    Cardellina, JH
    Monks, A
    Fisher, RJ
    Shoemaker, RH
    Melillo, G
    CANCER RESEARCH, 2005, 65 (19) : 9047 - 9055
  • [10] EFFECTS OF DNA-BINDING DRUGS ON TRANSCRIPTION
    CROTHERS, DM
    PHILLIPS, DR
    STRANEY, D
    STUDIA BIOPHYSICA, 1984, 104 (1-3): : 121 - 121
12345