Adherence to antiretroviral therapy, stigma and behavioral risk factors in HIV-infected adolescents in Asia

被引：15

作者：

Prasitsuebsai, Wasana ^{[1
]}

Sethaputra, Chuenkamol ^{[2
]}

Lumbiganon, Pagakrong ^{[3
]}

Hansudewechakul, Rawiwan ^{[4
]}

Chokephaibulkit, Kulkanya ^{[5
]}

Khanh Huu Truong ^{[6
]}

Lam Van Nguyen ^{[7
]}

Razali, Kamarul Azahar Mohd ^{[8
]}

Yusoff, Nik Khairulddin Nik ^{[9
]}

Fong, Moy Siew ^{[10
]}

Teeraananchai, Sirinya ^{[1
]}

Ananworanich, Jintanat ^{[11
,12
,13
,14
]}

Durier, Nicolas ^{[2
,15
]}

机构：

[1] Thai Red Cross AIDS Res Ctr, HIV Netherlands Australia Thailand Res Collaborat, Bangkok, Thailand

[2] TREAT Asia AmfAR, 388 Sukhumvit Rd,Suite 2104, Bangkok 10110, Klongtoey, Thailand

[3] Khon Kaen Univ, Srinagarind Hosp, Fac Med, Khon Kaen, Thailand

[4] Chiangrai Prachanukroh Hosp, Chiang Rai, Thailand

[5] Mahidol Univ, Fac Med, Siriraj Hosp, Bangkok, Thailand

[6] Childrens Hosp 1, Ho Chi Minh City, Vietnam

[7] Natl Hosp Pediat, Hanoi, Vietnam

[8] Hosp Kuala Lumpur, Inst Pediat, Kuala Lumpur, Malaysia

[9] Hosp Raja Perempuan Zainab II, Kelantan, Malaysia

[10] Hosp Likas, Kota Kinabalu, Malaysia

[11] Walter Reed Army Inst Res, US Mil HIV Res Program, Silver Spring, MD USA

[12] Henry M Jackson Fdn Adv Mil Med, Bethesda, MD USA

[13] Thai Red Cross AIDS Res Ctr, SEARCH, Bangkok, Thailand

[14] Univ Amsterdam, Amsterdam, Netherlands

[15] Dreamlopments LTD, Bangkok, Thailand

来源：

AIDS CARE-PSYCHOLOGICAL AND SOCIO-MEDICAL ASPECTS OF AIDS/HIV | 2018年 / 30卷 / 06期

基金：

美国国家卫生研究院;

关键词：

HIV; adolescents; Asia; adherence; stigma; MEDICATION ADHERENCE; SOCIAL SUPPORT; DISCLOSURE; CHILDREN; THAILAND; YOUTH; IMPACT; MULTISITE; HIV/AIDS; COHORT;

D O I：

10.1080/09540121.2018.1425363

中图分类号：

R19 [保健组织与事业（卫生事业管理）];

学科分类号：

摘要：

We studied behavioral risks among HIV-infected and uninfected adolescents using an audio computer-assisted self-interview. A prospective cohort study was initiated between 2013 and 2014 in Malaysia, Thailand, and Vietnam. HIV-infected adolescents were matched to uninfected adolescents (4:1) by sex and age group (12-14 and 15-18 years). We enrolled 250 HIV-infected (48% male; median age 14.5 years; 93% perinatally infected) and 59 uninfected (51% male; median age 14.1 years) adolescents. At enrollment, HIV-infected adolescents were on antiretroviral therapy (ART) for a median (IQR) of 7.5 (4.7-10.2) years, and 14% had HIV-RNA >1000copies/mL; 19% reported adherence <80%. Eighty-four (34%) HIV-infected and 26 (44%) uninfected adolescents reported having ever smoked cigarettes or drunk alcohol (p=0.13); 10% of HIV-infected and 17% of uninfected adolescents reported having initiated sexual activity; 6 of the HIV-infected adolescents had HIV-RNA >1000copies/mL. Risk behaviors were common among adolescents, with few differences between those with and without HIV.

引用

页码：727 / 733

页数：7

共 50 条

[1] Factors Influencing Adherence to Antiretroviral Therapy for HIV-Infected Female Inmates
Roberson, Donna W.
White, Becky L.
Fogel, Catherine I.
JANAC-JOURNAL OF THE ASSOCIATION OF NURSES IN AIDS CARE, 2009, 20 (01): : 50 - 61
[2] Risk factors for proteinuria in HIV-infected patients on antiretroviral therapy
Perez-Gonzalez, Y. S.
Mata-Marin, J. A.
ANTIVIRAL THERAPY, 2013, 18 : A82 - A82
[3] Risk factors for suboptimal antiretroviral therapy adherence in HIV-infected adolescents in Gaborone, Botswana: a pilot cross-sectional study
Ndiaye, Maimouna
Nyasulu, Peter
Hoang Nguyen
Lowenthal, Elizabeth D.
Gross, Robert
Mills, Edward J.
Nachega, Jean B.
PATIENT PREFERENCE AND ADHERENCE, 2013, 7 : 891 - 895
[4] Adherence with antiretroviral therapy in HIV-infected children.
Schuval, SJ
DeSarbo, J
Mamonluk, M
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1999, 103 (01) : S214 - S214
[5] Adherence to antiretroviral therapy in HIV-infected children in Italy
Albano, F
Spagnuolo, MI
Canani, RB
Guarino, A
AIDS CARE-PSYCHOLOGICAL AND SOCIO-MEDICAL ASPECTS OF AIDS/HIV, 1999, 11 (06): : 711 - 714
[6] Health literacy and antiretroviral adherence among HIV-infected adolescents
Murphy, Debra A.
Lam, Phebe
Naar-King, Sylvie
Harris, D. Robert
Parsons, Jeffrey T.
Muenz, Larry R.
PATIENT EDUCATION AND COUNSELING, 2010, 79 (01) : 25 - 29
[7] Predictors and Evolution of Antiretroviral Therapy Adherence Among Perinatally HIV-Infected Adolescents in Brazil
Cote, Jose
Delmas, Philippe
de Menezes Succi, Regina Celia
Galano, Eliana
Auger, Patricia
Sylvain, Helene
Colson, Sebastien
Machado, Daisy Maria
JOURNAL OF ADOLESCENT HEALTH, 2016, 59 (03) : 305 - 310
[8] Cardiovascular risk factors in HIV-infected patients on effective antiretroviral therapy
Tornero Estebanez, Carlos
Santamaria Martin, Alicia
Gil Tomas, Eva
Lapuebla Ferri, Consuelo
MEDICINA CLINICA, 2008, 130 (20): : 797 - 797
[9] Hepatotoxicity in HIV-infected children and adolescents on antiretroviral therapy
Mantes Gil, Am Cecilia
Lorenzetti, Raquel
Mendes, Gun Bergsten
Morcillo, Andre Moreno
Dalbo Contreras Toro, Adyleia Aparecida
Nolasco do Silva, Marcos Tadeu
dos Santos Vilela, Maria Marluce
SAO PAULO MEDICAL JOURNAL, 2007, 125 (04): : 205 - 209
[10] Guideline for Antiretroviral Therapy of HIV-Infected Children and Adolescents
Neubert, J.
Niehues, T.
Baumann, U.
Buchholz, B.
Notheiss, G.
Wintergerst, U.
Blume, J.
Feiterna-Sperling, C.
Laws, H. -J
Linde, R.
Koenigs, C.
KLINISCHE PADIATRIE, 2012, 224 (02): : 98 - 110

← 1 2 3 4 5 →