Organotin(iv) differential fluorescent probe for controlled subcellular localization and nuclear microviscosity monitoring

被引：4

作者：

Bernal-Escalante, Jasmine ^{[1
]}

Lopez-Vazquez, Armando ^{[1
]}

Araiza-Olivera, Daniela ^{[1
]}

Jimenez-Sanchez, Arturo ^{[1
]}

机构：

[1] Univ Nacl Autonoma Mexico, Inst Quim, Ciudad Univ,Circuito Exterior S-N, Mexico City 04510, DF, Mexico

来源：

CHEMICAL COMMUNICATIONS | 2019年 / 55卷 / 57期

关键词：

INTRAMOLECULAR PROTON-TRANSFER; CELL; TRANSITIONS; SENSOR; STATE;

D O I：

10.1039/c9cc04179f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A dual-emissive fluorescent probe enabling dynamic changes in nuclear local microviscosity monitoring was developed. The new sensing scenario involves probe subcellular localization redistribution, allowing a quantitative analysis of the local microviscosity related to nuclear damage in the presence of agents perturbing the nuclear morphology. With the aid of an organotin(iv) in situ formed complex we propose a different scenario of bioanalytical applications through confocal microscopy.

引用

页码：8246 / 8249

页数：4

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