Proposal of a comprehensive definition of modified and other forms of mycotoxins including "masked" mycotoxins

被引:249
|
作者
Rychlik, Michael [1 ,2 ]
Humpf, Hans-Ulrich [3 ]
Marko, Doris [4 ]
Daenicke, Sven [5 ]
Mally, Angela [6 ]
Berthiller, Franz [7 ,8 ]
Klaffke, Horst [9 ]
Lorenz, Nicole [9 ]
机构
[1] Tech Univ Munich, Chair Analyt Food Chem, D-85354 Freising Weihenstephan, Germany
[2] Tech Univ Munich, ZIEL Res Ctr Nutr & Food Sci, BIOANALYT Weihenstephan, D-85354 Freising Weihenstephan, Germany
[3] Univ Munster, Inst Food Chem, D-48161 Munster, Germany
[4] Univ Vienna, Inst Food Chem & Toxicol, A-1090 Vienna, Austria
[5] Friedrich Loeffler Inst, Fed Res Inst Anim Hlth, Inst Anim Nutr, D-38116 Braunschweig, Germany
[6] Univ Wurzburg, Dept Toxicol, D-97078 Wurzburg, Germany
[7] Univ Nat Resources & Life Sci, Christian Doppler Lab Mycotoxin Metab, Dept IFA Tulln, A-3430 Vienna, Tulln, Austria
[8] Univ Nat Resources & Life Sci, Ctr Analyt Chem, Dept IFA Tulln, A-3430 Vienna, Tulln, Austria
[9] BfR Fed Inst Risk Assessment, Safety Food Chain, Max Dohrn Str 8-10, D-10589 Berlin, Germany
关键词
Definition; Mycotoxins; Masked mycotoxins; Boundmycotoxins; Modified mycotoxins; Hidden mycotoxins; Conjugated mycotoxins; Mycotoxin metabolites; Mycotoxin derivatives; THERMAL-DEGRADATION PRODUCTS; FUMONISIN B-1; STRUCTURAL-CHARACTERIZATION; IMMUNOCHEMICAL METHODS; FUSARIUM MYCOTOXINS; NATURAL OCCURRENCE; MASS-SPECTROMETRY; CROSS-REACTIVITY; IN-VITRO; DEOXYNIVALENOL;
D O I
10.1007/s12550-014-0203-5
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
As the term "masked mycotoxins" encompasses only conjugated mycotoxins generated by plants and no other possible forms of mycotoxins and their modifications, we hereby propose for all these forms a systematic definition consisting of four hierarchic levels. The highest level differentiates the free and unmodified forms of mycotoxins from those being matrix-associated and from those being modified in their chemical structure. The following lower levels further differentiate, in particular, "modified mycotoxins" into "biologically modified" and "chemically modified" with all variations of metabolites of the former and dividing the latter into "thermally formed" and "non-thermally formed" ones. To harmonize future scientific wording and subsequent legislation, we suggest that the term "modified mycotoxins" should be used in the future and the term "masked mycotoxins" to be kept for the fraction of biologically modified mycotoxins that were conjugated by plants.
引用
收藏
页码:197 / 205
页数:9
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