New and improved ligands for highly enantioselective catalytic diphenylzinc additions to aryl aldehydes

被引：86
|
作者：
Huang, WS [1 ]
Pu, L [1 ]
机构：
[1] Univ Virginia, Dept Chem, Charlottesville, VA 22901 USA
来源：
TETRAHEDRON LETTERS | 2000年 / 41卷 / 02期
关键词：
D O I：
10.1016/S0040-4039(99)02041-9
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
By introducing electron-withdrawing fluorine atoms to a chiral 1,1'-binaphthyl ligand (R)-1, a new catalyst (S)-5d has been obtained which shows improved catalytic properties for the asymmetric diphenylzinc addition to aldehydes. This new ligand allows the synthesis of chiral diarylcarbinols with high enantioselectivity in shorter reaction time under simple reaction conditions. (C) 1999 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：145 / 149
页数：5
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