Synchronous ultrasonic Doppler imaging of magnetic microparticles in biological tissues

被引：8
|
作者：
Pyshnyi, Michael Ph. [1 ]
Kuznetsov, Oleg A. [1 ]
Pyshnaya, Svetlana V. [1 ]
Nechitailo, Galina S. [1 ]
Kuznetsov, Anatoly A. [1 ]
机构：
[1] Russian Acad Sci, Inst Biochem Phys, Moscow 119991, Russia
来源：
JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS | 2009年 / 321卷 / 10期
关键词：
New method; Synchronous ultrasonic Doppler imaging; Magnetic microsphere; Microparticles and nanoparticles; Soft biological tissue; Magnetic modulation; Ultrasound Doppler imaging; RADIOFREQUENCY-INDUCED HYPERTHERMIA; NANOPARTICLES;
D O I：
10.1016/j.jmmm.2009.02.084
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
We considered applicability of acoustic imaging technology for the detection of magnetic microparticles and nanoparticles inside soft biological tissues. Such particles are widely used for magnetically targeted drug delivery and magnetic hyperthermia. We developed a new method of ultrasonic synchronous tissue Doppler imaging with magnetic modulation for in vitro and in vivo detection and visualization of magnetic ultradisperse objects in soft tissues. Prototype hardware with appropriate software was produced and the method was successfully tested on magnetic microparticles injected into an excised pig liver. (c) 2009 Elsevier B.V. All rights reserved.
引用
收藏
页码：1552 / 1556
页数：5
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