Bortezomib plus melphalan and prednisone (VMP regimen) as the initial treatment for IgE multiple myeloma: a case study

被引:8
|
作者
Sato, Hiroyuki [1 ]
Komiya, Yusuke [1 ]
Hoshino, Shigeru [1 ]
机构
[1] Saitama Red Cross Hosp, Dept Hematol, Chuo Ku, Saitama 3388553, Japan
关键词
Multiple myeloma; IgE; Bortezomib; VMP regimen; Initial treatment; PLASMA-CELL LEUKEMIA; MAINTENANCE; THALIDOMIDE; EFFICACY; TRIAL; LEVEL; RARE;
D O I
10.1007/s12185-014-1571-5
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Patients with IgE multiple myeloma have poor prognosis. Due to the rarity of this condition, no standard treatment has been developed. As the VMP regimen (bortezomib plus melphalan and prednisone) has been reported to be highly effective in the treatment of other types of myeloma, we treated a patient with newly diagnosed IgE myeloma using the VMP regimen. Her myeloma responded well to VMP regimen. The results of this case report thus suggest that physicians may consider VMP regimen for use as the initial treatment for IgE myeloma.
引用
收藏
页码:786 / 789
页数:4
相关论文
共 50 条
  • [1] Bortezomib plus melphalan and prednisone (VMP regimen) as the initial treatment for IgE multiple myeloma: a case study
    Hiroyuki Sato
    Yusuke Komiya
    Shigeru Hoshino
    International Journal of Hematology, 2014, 99 : 786 - 789
  • [2] Bortezomib plus melphalan and prednisone for initial treatment of multiple myeloma
    San Miguel, Jesus F.
    Schlag, Rudolf
    Khuageva, Nuriet K.
    Dimopoulos, Meletios A.
    Shpilberg, Ofer
    Kropff, Martin
    Spicka, Ivan
    Petrucci, Maria T.
    Palumbo, Antonio
    Samoilova, Olga S.
    Dmoszynska, Anna
    Abdulkadyrov, Kudrat M.
    Schots, Rik
    Jiang, Bin
    Mateos, Maria-Victoria
    Anderson, Kenneth C.
    Esseltine, Dixie L.
    Liu, Kevin
    Cakana, Andrew
    van de Velde, Helgi
    Richardson, Paul G.
    NEW ENGLAND JOURNAL OF MEDICINE, 2008, 359 (09): : 906 - 917
  • [3] Bortezomib plus Melphalan and Prednisone for Multiple Myeloma
    Avvisati, Giuseppe
    NEW ENGLAND JOURNAL OF MEDICINE, 2008, 359 (24): : 2613 - 2613
  • [4] Bortezomib-Melphalan-Prednisone (VMP) Versus MP as Initial Treatment for Very Elderly Patients With Newly Diagnosed Multiple Myeloma
    Kim, Min Kyoung
    Kim, Kihyun
    Yoon, Do Hyun
    Suh, Cheolwon
    Moon, Joon Ho
    Lee, Yoo Jin
    Lee, Jae Hoon
    Jung, Sung-Hoon
    Lee, Je-Jung
    Kim, Hyo Jung
    Bae, Sung Hwa
    Kim, Jin Seok
    Lee, Jeong-Ok
    Eom, Hyeon Seok
    Lee, Won-Sik
    Kang, Hye Jin
    Mun, Yeung-Chul
    Do, Young Rok
    Hyun, Myung Soo
    CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2017, 17 (01): : E70 - E70
  • [5] DARATUMUMAB PLUS BORTEZOMIB, MELPHALAN, AND PREDNISONE (D-VMP) VERSUS BORTEZOMIB, MELPHALAN, AND PREDNISONE (VMP) IN NEWLY DIAGNOSED MULTIPLE MYELOMA (NDMM) PATIENTS (PTS) INELIGIBLE FOR TRANSPLANT: A PHASE 3 RANDOMIZED STUDY (ALCYONE)
    Mateos, M., V
    Dimopoulos, M. A.
    Cavo, M.
    Suzuki, K.
    Jakubowiak, A.
    Knop, S.
    Doyen, C.
    Lucio, P.
    Nagy, Z.
    Kaplan, P.
    Pou
    Cook, M.
    Grosicki, S.
    Crepaldi, A.
    Liberati, A. M.
    Campbell, P.
    Shelekhova, T.
    Yoon, S. S.
    Iosava, G.
    Fujisaki, T.
    Garg, M.
    Chiu, C.
    Wang, J.
    Carson, R.
    Crist, W.
    Deraedt, W.
    Nguyen, H.
    Qi, M.
    San-Miguel, J.
    HAEMATOLOGICA, 2018, 103 : 22 - 22
  • [6] Phase 3 Randomized Study of Daratumumab Plus Bortezomib, Melphalan, and Prednisone (D-VMP) Versus Bortezomib, Melphalan, and Prednisone (VMP) in Newly Diagnosed Multiple Myeloma (NDMM) Patients (Pts) Ineligible for Transplant (ALCYONE)
    Mateos, Maria-Victoria
    Dimopoulos, Meletios A.
    Cavo, Michele
    Suzuki, Kenshi
    Jakubowiak, Andrzej J.
    Knop, Stefan
    Doyen, Chantal
    Lucio, Paulo
    Nagy, Zsolt
    Kaplan, Polina
    Pour, Ludek
    Cook, Mark
    Grosicki, Sebastian
    Crepaldi, Andre H.
    Liberati, Anna Marina
    Campbell, Philip
    Shelekhova, Tatiana
    Yoon, Sung-Soo
    Iosava, Genadi
    Fujisaki, Tomoaki
    Garg, Mamta
    Chiu, Christopher
    Wang, Jianping
    Carson, Robin
    Crist, Wendy
    Deraedt, William
    Nguyen, Marie
    Qi, Ming
    San-Miguel, Jesus F.
    BLOOD, 2017, 130
  • [7] Efficacy and safety of Daratumumab, Bortezomib, Melphalan, and Prednisone (D-VMP) versus Bortezomib, Melphalan, and Prednisone (VMP) in Chinese patients with newly diagnosed Multiple Myeloma: OCTANS
    Fu, Weijun
    Huang, Honghui
    Li, Wei
    An, Gang
    Cai, Zhen
    Jin, Jie
    Wang, Yafei
    Chim, Chor Sang
    Qi, Ming
    Wang, Jianping
    Song, Yang
    Jia, Bin
    Yang, Xue
    Liu, Wenyu
    Li, Yunan
    Zhang, Renyi
    Hou, Jian
    Wang, Jianxiang
    CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2021, 21 : S125 - S125
  • [8] Bortezomib, melphalan, prednisone (VMP) versus melphalan, prednisone, thalidomide (MPT) in elderly newly diagnosed multiple myeloma patients: A retrospective case-matched study
    Morabito, Fortunato
    Bringhen, Sara
    Larocca, Alessandra
    Wijermans, Pierre
    Victoria Mateos, Maria
    Gimsing, Peter
    Mazzone, Carla
    Gottardi, Daniela
    Omede, Paola
    Zweegman, Sonja
    Jose Lahuerta, Juan
    Zambello, Renato
    Musto, Pellegrino
    Magarotto, Valeria
    Schaafsma, Martijn
    Oriol, Albert
    Juliusson, Gunnar
    Cerrato, Chiara
    Catalano, Lucio
    Gentile, Massimo
    Isabel Turel, Ana
    Liberati, Anna Marina
    Cavalli, Maide
    Rossi, Davide
    Passera, Roberto
    Rosso, Stefano
    Beksac, Meral
    Cavo, Michele
    Waage, Anders
    San Miguel, Jesus
    Boccadoro, Mario
    Sonneveld, Pieter
    Palumbo, Antonio
    Offidani, Massimo
    AMERICAN JOURNAL OF HEMATOLOGY, 2014, 89 (04) : 355 - 362
  • [9] The Cost-Effectiveness of Initial Treatment of Multiple Myeloma in the U.S. With Bortezomib Plus Melphalan and Prednisone Versus Thalidomide Plus Melphalan and Prednisone or Lenalidomide Plus Melphalan and Prednisone With Continuous Lenalidomide Maintenance Treatment
    Garrison, Louis P., Jr.
    Wang, Si-Tien
    Huang, Hui
    Ba-Mancini, Abbie
    Shi, Hongliang
    Chen, Kristina
    Korves, Caroline
    Dhawan, Ravinder
    Cakana, Andrew
    van de Velde, Helgi
    Corzo, Deyanira
    Duh, Mei Sheng
    ONCOLOGIST, 2013, 18 (01): : 27 - 36
  • [10] Copy Number Variations Could Predict the Outcome of Bortezomib Plus Melphalan and Prednisone for Initial Treatment of Multiple Myeloma
    Kim, Myungshin
    Lee, Shin Hyo
    Kim, Jiyeon
    Lee, Sung-Eun
    Kim, Yoo-Jin
    Min, Chang-Ki
    GENES CHROMOSOMES & CANCER, 2015, 54 (01): : 20 - 27