Modulating Nanoparticle Translocation by Surface Chemistry of Gold Nanopores

被引：2
|
作者：
Liu Ao-Xue [1 ]
Yang Dan [1 ]
Li Hong-Na [1 ]
Liu Guo-Hui [1 ]
Fu Qiang [2 ]
Shan Yu-Ping [1 ]
Yang Guo-Cheng [1 ]
He Jin [1 ]
机构：
[1] Changchun Univ Technol, Sch Chem & Life Sci, Adv Inst Mat Sci, Changchun 130012, Jilin, Peoples R China
[2] Jiangxi Coll Tradit Chinese Med, Fuzhou 344000, Fujian, Peoples R China
来源：
CHINESE JOURNAL OF ANALYTICAL CHEMISTRY | 2019年 / 47卷 / 07期
基金：
中国国家自然科学基金;
关键词：
Nanopipette; Gold nanopore; Nanoparticles; Chemical modification; Dielectrophoretic trapping; IONIC CURRENT RECTIFICATION; SINGLE;
D O I：
10.1016/S1872-2040(19)61174-6
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
A simple and effective method for modulating nanoparticles (NPs) translocation through nanopore by tuning the surface change of chemically modified gold coated nanopore was developed. The gold-coated pore is simply prepared from a nanopipette and the partially insulated gold coating can be utilized to effectively concentrate NPs near the nanopore entrance. The surface modification of gold near the orifice effectively modulates the NP translocation behavior, mainly through electrostatic force and chemical interactions. This system can be extended to the detection of biological entities, such as virus and exosomes which have similar size of NPs.
引用
收藏
页码：e19081 / e19087
页数：7
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