First Synthesis of Thiophene Thioglycosides

被引：25

作者：

Elgemeie, Galal H. ^{[1
]}

Zaghary, Wafaa A. ^{[2
]}

Amin, Kamelia M. ^{[3
]}

Nasr, Tamer M. ^{[2
]}

机构：

[1] Helwan Univ, Fac Sci, Dept Chem, Cairo, Egypt

[2] Helwan Univ, Dept Pharmaceut Chem, Fac Pharm, Cairo, Egypt

[3] Cairo Univ, Dept Pharmaceut Chem, Fac Pharm, Cairo, Egypt

来源：

JOURNAL OF CARBOHYDRATE CHEMISTRY | 2009年 / 28卷 / 03期

关键词：

Thiophene thioglycosides; Sodium thiophenethiolate; Galacto-pyranosyl bromides; NUCLEOSIDES;

D O I：

10.1080/07328300902789209

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A new method for the preparation of a new class of thiophene thioglycosides via one-pot reaction of the sodium thiophenethiolate salts with 2,3,4,6-tetra-O-acetyl--D-gluco- and galacto-pyranosyl bromides has been studied. The sodium thiophenethiolate salts are prepared using cyano-di-thioic analogs and their corresponding mono- and dithiolate salts.

引用

页码：161 / 178

页数：18

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