False dawn for cystic fibrosis disease modifiers?

被引:2
|
作者
Holmes, David
机构
关键词
D O I
10.1038/nrd4456
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Recent results have cast doubt over how effective a breakthrough class of cystic fibrosis drugs can be in patients with the most common form of the disease.
引用
收藏
页码:713 / 714
页数:2
相关论文
共 50 条
  • [1] False dawn for cystic fibrosis disease modifiers?
    David Holmes
    Nature Reviews Drug Discovery, 2014, 13 : 713 - 714
  • [2] Genetic Modifiers of Liver Disease in Cystic Fibrosis
    Bartlett, Jaclyn R.
    Friedman, Kenneth J.
    Ling, Simon C.
    Pace, Rhonda G.
    Bell, Scott C.
    Bourke, Billy
    Castaldo, Giuseppe
    Castellani, Carlo
    Cipolli, Marco
    Colombo, Carla
    Colombo, John L.
    Debray, Dominique
    Fernandez, Adriana
    Lacaille, Florence
    Macek, Milan, Jr.
    Rowland, Marion
    Salvatore, Francesco
    Taylor, Christopher J.
    Wainwright, Claire
    Wilschanski, Michael
    Zemkova, Dana
    Hannah, William B.
    Phillips, M. James
    Corey, Mary
    Zielenski, Julian
    Dorfman, Ruslan
    Wang, Yunfei
    Zou, Fei
    Silverman, Lawrence M.
    Drumm, Mitchell L.
    Wright, Fred A.
    Lange, Ethan M.
    Durie, Peter R.
    Knowles, Michael R.
    Clancy, J. P.
    Sindel, L. J.
    Roberts, D. M.
    Roberts, V.
    Radford, P. J.
    Argel, N.
    Morgan, W. J.
    Douthit, J. L.
    Schellhase, D. E.
    Anderson, P.
    Taggart, A.
    Morrissey, B.
    Platzker, A. C. G.
    Woo, M. S.
    Fukushima, L.
    Hsu, E.
    JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2009, 302 (10): : 1076 - 1083
  • [3] Genetic modifiers of lung disease in cystic fibrosis
    Drumm, ML
    Konstan, MW
    Schluchter, MD
    Handler, A
    Pace, R
    Zou, F
    Zariwala, M
    Fargo, D
    Xu, AR
    Dunn, JM
    Darrah, RJ
    Dorfman, R
    Sandford, AJ
    Corey, M
    Zielenski, J
    Durie, P
    Goddard, K
    Yankaskas, JR
    Wright, FA
    Knowles, MR
    NEW ENGLAND JOURNAL OF MEDICINE, 2005, 353 (14): : 1443 - 1453
  • [4] Cystic Fibrosis: Using genetic association to identify modifiers of disease variability in cystic fibrosis
    Garry R Cutting
    European Journal of Human Genetics, 2006, 14 : 890 - 891
  • [5] Genetic Modifiers of Cystic Fibrosis Lung Disease Severity
    Zhou, Yi-Hui
    Gallins, Paul J.
    Pace, Rhonda G.
    Dang, Hong
    Aksit, Melis A.
    Blue, Elizabeth E.
    Buckingham, Kati J.
    Collaco, Joseph M.
    Faino, Anna V.
    Gordon, William W.
    Hetrick, Kurt N.
    Ling, Hua
    Liu, Weifang
    Onchiri, Frankline M.
    Pagel, Kymberleigh
    Pugh, Elizabeth W.
    Raraigh, Karen S.
    Rosenfeld, Margaret
    Sun, Quan
    Wen, Jia
    Li, Yun
    Corvol, Harriet
    Strug, Lisa J.
    Bamshad, Michael J.
    Blackman, Scott M.
    Cutting, Garry R.
    Gibson, Ronald L.
    O'Neal, Wanda K.
    Wright, Fred A.
    Knowles, Michael R.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2023, 207 (10) : 1324 - 1333
  • [6] Genetic modifiers in cystic fibrosis
    Rossi, G
    Rossi, V
    NEW ENGLAND JOURNAL OF MEDICINE, 2006, 354 (01): : 89 - 89
  • [7] Gene modifiers in cystic fibrosis
    Accurso, Frank J.
    Sontag, Marci K.
    JOURNAL OF CLINICAL INVESTIGATION, 2008, 118 (03): : 839 - 841
  • [8] Evidence for genetic modifiers of cystic fibrosis lung disease.
    Marsick, RJ
    Drumm, ML
    AMERICAN JOURNAL OF HUMAN GENETICS, 2000, 67 (04) : 334 - 334
  • [9] GENETIC MARKERS AND MODIFIERS OF GASTROINTESTINAL DISEASE AND NUTRITION IN CYSTIC FIBROSIS
    Durie, Peter R.
    PEDIATRIC PULMONOLOGY, 2013, 48 : 124 - 125
  • [10] Gene modifiers of cystic fibrosis lung disease: A systematic review
    Shanthikumar, Shivanthan
    Neeland, Melanie N.
    Saffery, Richard
    Ranganathan, Sarath
    PEDIATRIC PULMONOLOGY, 2019, 54 (09) : 1356 - 1366