Synthesis and antibacterial activity of 5-aryl-2-acyl thio-1,3,4-oxadiazoles

被引：0
|
作者：
Jain, S [1 ]
Mishra, P
机构：
[1] Guru Jambheshwar Univ, Dept Pharmaceut Sci, Hisar 125001, Haryana, India
[2] Dr Hari Singh Gour Vishwavidyalaya, Dept Pharmaceut Sci, Sagar 470003, India
来源：
INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY | 2004年 / 13卷 / 04期
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中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Aromatic carboxylic acid hydrazides (I) on refluxing with carbon disulfide and methanolic potassium hydroxide and then subsequent acidification with hydrochloric acid furnish 5-aryl-1,3,4-oxadiazole-2-thiones (II). Acyl chlorides (III) react with (II) to yield the title compounds (IV). All the compounds were screened for their in vivo antibacterial activity.
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页码：307 / 310
页数：4
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