Ultrasonic and Grinding Aptitudes of One-Pot Synthesis of 5-(4-Chlorophenyl)-7-(3,4-Dimethyl Phenyl)-2-oxo-2H-Pyrano[2,3-b]Pyridine Derivatives as Antibacterial Agents

被引:17
|
作者
Rizk, Sameh A. [1 ]
El-Hashash, Maher A. [1 ]
El-Badawy, Azza A. [1 ]
机构
[1] Ain Shams Univ, Fac Sci, Dept Chem, Cairo 11566, Egypt
关键词
PHOTOLABILE PROTECTING GROUPS; DIELS-ALDER REACTIONS; BIOLOGICAL EVALUATION; CHALCONE DERIVATIVES; EFFICIENT; CELLS; PALLADIUM(II); INHIBITORS; COMPLEXES; CHEMISTRY;
D O I
10.1002/jhet.2797
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A simple facile one-pot synthesis of 5-(4-chlorophenyl)-7-(3,4-dimethyl phenyl)-2-oxo-2H-pyrano[2,3-b]pyridine derivatives via three-component reaction of chalcone, ethyl-2-substituted acetate, and ammonium acetate under ultrasonic irradiation and grinding tools. The newly synthesized compounds were evaluated for their antibacterial activity against ATCC 25923, ATCC 10987, ATCC 274, and SM514. All the synthesized compounds have been characterized on the basis of their elemental analyses and spectral data.
引用
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页码:2003 / 2011
页数:9
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