Bi-directional activation of inflammation and coagulation in septic neonates

被引:6
|
作者
Del Vecchio, Antonio [1 ]
Stronati, Mauro [2 ]
Franco, Caterina [1 ]
Christensen, Robert D. [3 ]
机构
[1] Di Venere Hosp, Div Neonatol, Neonatal Intens Care Unit, I-70121 Bari, Italy
[2] Fdn IRCCS Policlin San Matteo, Maternal Infant Dept, Neonatal Intens Care Unit, Pavia, Italy
[3] Intermt Healthcare, Women & Newborns Program, Salt Lake City, UT USA
关键词
Neonate; Sepsis; Coagulation; Inflammatory cytokines; Inflammation; PROTEIN-C; HEMOSTASIS; SYSTEM; SEPSIS; TERM;
D O I
10.1016/S0378-3782(14)70008-8
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Neonatal sepsis is frequently accompaniedby significant and sometimes life-threatening coagulopathy. More complete understanding is needed of the molecular and cellular mechanisms underlying the interaction of the inflammatory and hemostatic systems. Such information may help focus future studies toward novel ways to improve the outcome of neonates who develop septic coagulopathy. (C) 2014 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:S22 / S25
页数:4
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