pH-Induced Reorganization and Membrane Insertion of the Diphtheria Toxin T-Domain Studied by Spr and Neutron Reflectometry

被引：0
|
作者：
Eells, Rebecca [1 ]
Heinirch, Frank [1 ,2 ]
Loesche, Mathias [1 ,2 ]
Rodnin, Mykola V. [3 ]
Ladokhin, Alexey S. [3 ]
机构：
[1] Carnegie Mellon Univ, Dept Phys, Pittsburgh, PA 15213 USA
[2] NIST, Ctr Neutron Res, Gaithersburg, MD 20899 USA
[3] KUMC, Dept Biochem & Mol Biol, Kansas City, KS USA
来源：
BIOPHYSICAL JOURNAL | 2015年 / 108卷 / 02期
关键词：
D O I：
10.1016/j.bpj.2014.11.3056
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
2826-Pos
引用
收藏
页码：557A / 557A
页数：1
相关论文
共 35 条
  • [1] Thermodynamics of Membrane Insertion and Refolding of the Diphtheria Toxin T-Domain
    Vargas-Uribe, Mauricio
    Rodnin, Mykola V.
    Ojemalm, Karin
    Holgado, Aurora
    Kyrychenko, Alexander
    Nilsson, IngMarie
    Posokhov, Yevgen O.
    Makhatadze, George
    von Heijne, Gunnar
    Ladokhin, Alexey S.
    JOURNAL OF MEMBRANE BIOLOGY, 2015, 248 (03): : 383 - 394
  • [2] Thermodynamics of Membrane Insertion and Refolding of the Diphtheria Toxin T-Domain
    Mauricio Vargas-Uribe
    Mykola V. Rodnin
    Karin Öjemalm
    Aurora Holgado
    Alexander Kyrychenko
    IngMarie Nilsson
    Yevgen O. Posokhov
    George Makhatadze
    Gunnar von Heijne
    Alexey S. Ladokhin
    The Journal of Membrane Biology, 2015, 248 : 383 - 394
  • [3] Kinetic and Thermodynamic Studies of pH-Triggered Membrane Insertion of Diphtheria Toxin T-Domain
    Kyrychenko, Alexander
    Rodnin, Mykola V.
    Posokhov, Yevgen O.
    Thoma, Anna
    Brettmann, Joshua
    Ladokhin, Alexey S.
    BIOPHYSICAL JOURNAL, 2010, 98 (03) : 485A - 485A
  • [4] pH-Triggered Conformational Switching along the Membrane Insertion Pathway of the Diphtheria Toxin T-Domain
    Ladokhin, Alexey S.
    TOXINS, 2013, 5 (08): : 1362 - 1380
  • [5] pH-Triggered Membrane Insertion Pathway of the Diphtheria Toxin T-Domain: 1. Insertion/Refolding Intermediate
    Kyrychenko, Alexander
    Rodnin, Mykola V.
    Posokhov, Yevgen O.
    Ladokhin, Alexey S.
    BIOPHYSICAL JOURNAL, 2009, 96 (03) : 433A - 433A
  • [6] Thermodynamic and Kinetic Analysis of Membrane Protein Insertion: Case of Diphtheria Toxin T-Domain
    Ladokhin, Alexey S.
    Brettmann, Joshua
    Kyrychenko, Alexander
    Posokhov, Yevgen O.
    Rodnin, Mykola V.
    Thoma, Anna
    FASEB JOURNAL, 2010, 24
  • [7] pH-Triggered Membrane Insertion Pathway of the Diphtheria Toxin T-Domain: 2. Role of Histidines
    Rodnin, Mykola V.
    Kyrychenko, Alexander
    Posokhov, Yevgen O.
    Brettmann, Joshua
    Thoma, Anna
    Ladokhin, Alexey S.
    BIOPHYSICAL JOURNAL, 2009, 96 (03) : 433A - 433A
  • [8] Multiscale Simulations of Diphtheria Toxin T-Domain Membrane Association
    Flores-Canales, Jose C.
    Ladokhin, Alexey S.
    Kurnikova, Maria
    BIOPHYSICAL JOURNAL, 2014, 106 (02) : 441A - 441A
  • [9] Deciphering Membrane Insertion of the Diphtheria Toxin T Domain by Specular Neutron Reflectometry and Solid-State NMR Spectroscopy
    Chenal, Alexandre
    Prongidi-Fix, Lydia
    Perier, Aurelie
    Aisenbrey, Christopher
    Vernier, Gregory
    Lambotte, Stephan
    Fragneto, Giovanna
    Bechinger, Burkhard
    Gillet, Daniel
    Forge, Vincent
    Ferrand, Michel
    JOURNAL OF MOLECULAR BIOLOGY, 2009, 391 (05) : 872 - 883
  • [10] Kinetic Intermediate Reveals Staggered pH-Dependent Transitions along the Membrane Insertion Pathway of the Diphtheria Toxin T-Domain
    Kyrychenko, Alexander
    Posokhov, Yevgen O.
    Rodnin, Mykola V.
    Ladokhin, Alexey S.
    BIOCHEMISTRY, 2009, 48 (32) : 7584 - 7594
1234