A practical regiospecific synthesis of 9-nitrocamptothecin

被引：3
|
作者：
Fu, QingQuan
Chen, Zhiyong
机构：
[1] Chinese Acad Sci, Chengdu Inst Organ Chem, Key Lab Asymmet Synth & Chirotechnol Sichuan Prov, Chengdu 610041, Peoples R China
[2] Chinese Acad Sci, Chengdu Inst Organ Chem, Union Lab Asymmetr Synth, Chengdu 610041, Peoples R China
[3] Chinese Acad Sci, Grad Sch, Beijing 10049, Peoples R China
来源：
SYNTHESIS-STUTTGART | 2006年 / 12期
关键词：
9-nitrocamptothecin; nitration; reduction of sulfonate;
D O I：
10.1055/s-2006-942359
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
9-Nitrocamptothecin has shown potent antitumor activity against many types of human cancers. A practical scale-up procedure for this compound is reported by selective reduction of corresponding sulfonate.
引用
收藏
页码：1940 / 1942
页数：3
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