Biomimetic syntheses of lamellarin and lukianol-type alkaloids

被引：43
|
作者：
Peschko, Christian [1 ]
Winklhofer, Christian [1 ]
Terpin, Andreas [1 ]
Steglich, Wolfgang [1 ]
机构：
[1] Univ Munich, Dept Chem, D-81377 Munich, Germany
来源：
SYNTHESIS-STUTTGART | 2006年 / 18期
关键词：
biomimetic synthesis; marine alkaloids; pyrroles; lamellarins; lukianol A;
D O I：
10.1055/s-2006-950191
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The formation of 3,4-diarylpyrrole-2,5-dicarboxylic acids from arylpyruvic acids and 2-arylethylamines was used as a key step for the synthesis of several marine pyrrole alkaloids. The utility of this method is illustrated through the development of syntheses of ningalin B (5), lamellarins G (11a) and K (11b), lukianol A (32), and a lukianol-lamellarin hybrid (24).
引用
收藏
页码：3048 / 3057
页数：10
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