Opinion - Yeast as a model system for anticancer drug discovery

被引：76
|
作者：
Simon, JA
Bedalov, A
机构：
[1] Fred Hutchinson Canc Res Ctr, Div Clin Res, Seattle, WA 98104 USA
[2] Fred Hutchinson Canc Res Ctr, Human Biol Div, Seattle, WA 98104 USA
来源：
NATURE REVIEWS CANCER | 2004年 / 4卷 / 06期
关键词：
D O I：
10.1038/nrc1372
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Yeast is widely used as a model organism for investigating many aspects of eukaryotic cell biology. It combines a high level of conservation between its cellular processes and those of mammalian cells with advantages such as simple growth requirements, rapid cell division, ease of genetic manipulation and a wealth of experimental tools for genome-wide analysis of biological functions. How can these advantages be put to use in anticancer drug discovery?
引用
收藏
页码：481 / 488
页数：8
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