Effect of superoxide dismutase deficiency on the life span of the yeast Saccharomyces cervisiae.: An oxygen-independent role of Cu,Zn-superoxide dismutase

被引：25
|
作者：
Wawryn, J
Swiecilo, A
Bartosz, G
Bilinski, T
机构：
[1] Univ Rzeszow, Dept Cell Biochem & Biol, PL-35310 Rzeszow, Poland
[2] Zamosc Coll Agr, PL-22400 Zamosc, Poland
来源：
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS | 2002年 / 1570卷 / 03期
关键词：
aging; yeast; Saccharomyces cerevisiae; superoxide dismutase; hypoxia; anoxia;
D O I：
10.1016/S0304-4165(02)00197-6
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Effects of the absence of Cu,Zn-superoxide dismutase (CuZnSOD) on the replicative life span of the yeast Saccharomyces cerevisiae were studied under different oxygen conditions. In both strains, replicative life span and the rate of cell divisions were found to be similar under the atmosphere of air and under hypoxic (3% oxygen) and anoxic conditions. These results indicate that deleterious consequences of the lack of CuZnSOD are not limited to elevation of superoxide concentration and involve function(s) other than superoxide scavenging. (C) 2002 Published by Elsevier Science B.V.
引用
收藏
页码：199 / 202
页数：4
相关论文
共 50 条
  • [1] Cu, Zn-superoxide dismutase of Saccharomyces cerevisiae is required for resistance to hyperosmosis
    Garay-Arroyo, A
    Lledías, F
    Hansberg, W
    Covarrubias, AA
    [J]. FEBS LETTERS, 2003, 539 (1-3): : 68 - 72
  • [2] REGULATION OF CU,ZN-SUPEROXIDE AND MN-SUPEROXIDE DISMUTASE TRANSCRIPTION IN SACCHAROMYCES-CEREVISIAE
    GALIAZZO, F
    LABBEBOIS, R
    [J]. FEBS LETTERS, 1993, 315 (02) : 197 - 200
  • [3] Putative denitrosylase activity of Cu,Zn-superoxide dismutase
    Okado-Matsumoto, Ayako
    Fridovich, Irwin
    [J]. FREE RADICAL BIOLOGY AND MEDICINE, 2007, 43 (05) : 830 - 836
  • [4] Putative denitrosylase activity of Cu, Zn-superoxide dismutase
    Okado-Matsumoto, Ayako
    Fridovich, Irwin
    [J]. FREE RADICAL BIOLOGY AND MEDICINE, 2007, 43 : S32 - S32
  • [5] Modification of Cu,Zn-superoxide dismutase by oxidized catecholamines
    Kang, JH
    [J]. JOURNAL OF BIOCHEMISTRY AND MOLECULAR BIOLOGY, 2004, 37 (03): : 325 - 329
  • [6] Structural Consequences of Cysteinylation of Cu/Zn-Superoxide Dismutase
    Auclair, Jared R.
    Brodkin, Heather R.
    D'Aquino, J. Alejandro
    Petsko, Gregory A.
    Ringe, Dagmar
    Agar, Jeffrey N.
    [J]. BIOCHEMISTRY, 2013, 52 (36) : 6145 - 6150
  • [7] Yeast Saccharomyces cerevisiae devoid of Cu, Zn-superoxide dismutase as a cellular model to study acrylamide toxicity
    Kwolek-Mirek, Magdalena
    Zadrag-Tecza, Renata
    Bednarska, Sabina
    Bartosz, Grzegorz
    [J]. TOXICOLOGY IN VITRO, 2011, 25 (02) : 573 - 579
  • [8] Functional mimics of Cu, Zn-superoxide dismutase enzymes
    Bonomo, RP
    Impellizzeri, G
    La Mendola, D
    Maccarrone, G
    Pappalardo, G
    Santoro, A
    Tabbi, G
    Vecchio, G
    Rizzarelli, E
    [J]. METAL-LIGAND INTERACTIONS: MOLECULAR, NANO-, MICRO-, AND MACRO-SYSTEMS IN COMPLEX ENVIRONMENTS, 2003, 116 : 41 - 63
  • [9] Peroxidative activity of human Cu,Zn-superoxide dismutase
    Kim, SM
    Kang, JH
    [J]. MOLECULES AND CELLS, 1997, 7 (01) : 120 - 124
  • [10] The Activation Mechanism of Bacterial Cu,Zn-Superoxide Dismutase
    Sakurai, Y.
    Furukawa, Y.
    [J]. JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, 2014, 19 : S256 - S256
12345