A synthesis of (4S)-2-(acetoxymethyl)-4(tert-butyl-diphenylsilyloxy)-2-cyclopenten-1-one

被引：2
|
作者：
Shi, XX
Wu, QQ
Lu, X
机构：
[1] E China Univ Sci & Technol, Fac Chem & Pharmaceut Engn, Shanghai 200237, Peoples R China
[2] Chinese Acad Sci, Shanghai Inst Organ Chem, Shanghai 200032, Peoples R China
来源：
TETRAHEDRON-ASYMMETRY | 2002年 / 13卷 / 05期
基金：
中国国家自然科学基金;
关键词：
D O I：
10.1016/S0957-4166(02)00145-3
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
We describe: here a synthesis of (4S)-2-(acetoxymethyl)-4-(tert-butyldiphenylsilyloxy)-2-cyclopenten-1-one 1 from L-malic acid in seven steps via an intramolecular aldolization-dehydration cyclization reaction of the acyclic 1,6-dialdehyde 10. The conditions of the intramolecular aldolization-dehydration cyclization reaction were also optimized. (C) 2002 Published by Elsevier Science Ltd.
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页码：461 / 464
页数：4
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