(3aS,7aS)-1-{2-Oxo-1,3-bis[(S)-1-phenylethyl]perhydro-1,3,2λ5-benzodiazaphosphol-2-yl}-l-phenylmethanol:: a mixture of diastereoisomers in a disordered crystal

被引：2
|
作者：
Moreno, GE
Quintero, L
Bernès, S
de Parrodi, CA
机构：
[1] Univ Autonoma Puebla, Inst Ciencias, Ctr Quim, Puebla 72000, Mexico
[2] Univ Autonoma Puebla, Fac Ciencias Quim, Ctr Invest, Puebla 72001, Mexico
[3] Univ Americas Puebla, Ctr Invest Quim Biol, Puebla 72820, Mexico
来源：
ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY | 2004年 / 60卷 / 06期
关键词：
D O I：
10.1107/S0108270104008492
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
In the title compound, C29H35N2O2P, the stereogenic C center alpha to the P atom, formed during the Pudovik condensation reaction between a deprotonated chiral diazaphosphole and benzaldehyde, has disordered substituents, giving a mixture of Calpha-R and Calpha-S diastereoisomers. Moreover, this compound crystallizes with two independent molecules in the asymmetric unit. The observed configuration at the Calpha atom is 0.741 (6)-S mixed with 0.259 (6)-R, indicating diastereoisomeric enrichment during crystallization. Data from solution and solid-state studies consistently point to an epimerization process at the Calpha atom.
引用
收藏
页码：O411 / O414
页数：4
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