Study on the binding effect between cordycepin and calf thymus DNA by circular dichroism

被引：0
|
作者：
Ling, Jian Ya [1 ]
Lin, Jian Qun
Zhang, Guo Ying
Zhang, Chang Kai
机构：
[1] Shandong Univ, State Key Lab Microbial Technol, Jinan 250100, Peoples R China
[2] Shandong Univ, Sch Environm Sci & Engn, Jinan 250100, Peoples R China
[3] Shandong Univ, Tradit Chinese Med, Jinan 250014, Peoples R China
来源：
CHINESE CHEMICAL LETTERS | 2006年 / 17卷 / 10期
关键词：
cordycepin; DNA-binding; CT-DNA; conformation; spectroscopic technique;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Binding of cordycepin to the double helical DNA with a high affinity was investigated by CD spectra in this paper. The results proved that uncoiling, unbinding and denaturation of DNA proceeded continuously upon the increase of the concentration of cordycepin.
引用
收藏
页码：1351 / 1352
页数：2
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